Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy
Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth +4 more
wiley +1 more source
The Effect of von Willebrand Disease on Platelet Adhesion Dynamics: Correlating a Multiscale Platelet Model to In Vitro Results. [PDF]
Wang P, Sheriff J, Deng Y, Bluestein D.
europepmc +1 more source
Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold +9 more
wiley +1 more source
Endothelial β-PIX (ARHGEF7) supports actomyosin mediated expulsion of VWF through dynamic reorganization of the cytoskeleton. [PDF]
El-Mansi S, Deegan KM, Nightingale TD.
europepmc +1 more source
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai +7 more
wiley +1 more source
Targeted proteomics of extreme vascular phenotypes in type 1 diabetes: the ESCAPER study. [PDF]
Ekström O +7 more
europepmc +1 more source
The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models
This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva +5 more
wiley +1 more source
Transcriptomic and Proteomic Analyses Identify THBS2, VWF, NFASC, and AKR1B10 as Diagnostic Biomarkers for Advanced Fibrosis in NAFLD. [PDF]
Ding S, Liu Y, Liu Z, Chu F, Lu B, Xu L.
europepmc +1 more source
Understanding exosomes in diabetic wound healing
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
Chronic Iron Deficiency Anemia as the Initial Manifestation of Undiagnosed Von Willebrand Disease in a Woman With Long-Standing Menorrhagia: A Case Report. [PDF]
Rafique S, Rafiq I.
europepmc +1 more source

