Results 101 to 110 of about 60,736 (289)

Autosomal dominant C1149R von Willebrand disease: phenotypic findings and their implications

Haematologica, 2009
Background Mutation C1149R in the von Willebrand factor (VWF) gene has been thought to cause autosomal dominant severe type 1 von Willebrand disease (VWD).Design and Methods Eight patients from three unrelated families with this mutation were included in
Almudena Pérez-Rodríguez, Aranzazu García-Rivero, Esther Lourés, Maria Fernanda López-Fernández, Angela Rodríguez-Trillo, Javier Batlle   +5 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Reference intervals for active VWF and other VWF parameters in 120 healthy individuals.

, 2019
Reference intervals for active VWF and other VWF parameters in 120 healthy individuals.
Jasper A. Remijn (6331226), Hilde Kelchtermans (12561), Philip G. de Groot (167182), Lisa N. van der Vorm (6331220), Dana Huskens (211452), Walid Chayouâ (6331223), Bas de Laat (339246), Li Li (14993), Mark Roest (377867)   +8 more
core   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Summary of 8 mAbs to VWF and their effects on VWF proteolysis by ADAMTS13.

, 2013
Summary of 8 mAbs to VWF and their effects on VWF proteolysis by ADAMTS13.
Ningzheng Dong (328283), Changgeng Ruan (328282), Jingyu Zhang (256203), Yiming Zhao (348349), Zhenni Ma (328280), Jian Su (86223), Anyou Wang (281729), Fang Liu (13271), Fei Shen (348351)   +8 more
core   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Impact of extracorporeal membrane oxygenation treatments on acquired von Willebrand syndrome in patients with out-of-hospital cardiac arrest: a retrospective observational study

Thrombosis Journal
Background Von Willebrand factor (vWF) plays a crucial role in hemostasis, acting as a key factor for platelet adhesion/aggregation and as a transport protein for coagulation factor VIII. vWF is secreted as a giant multimer, and it undergoes shear stress-
Yuki Chiba, Kota Goto, Misako Suzuki, Hisanori Horiuchi, Mineji Hayakawa   +4 more
doaj   +1 more source

vWF Alignment

, 2013
Nexus file containing phased alleles from vWF sequences of Javan Crocidura.
Jacob A. Esselstyn (214666), Anang S. Achmadi (3199698), Evans, Ben J., Esselstyn, Jacob A., Maharadatunkamsi, -, Siler, Cameron D., Ben J. Evans (270416), - Maharadatunkamsi (3245379), Cameron D. Siler (618179), Achmadi, Anang S.   +9 more
core   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source