Results 271 to 280 of about 81,482 (329)

Single-domain antibodies for brain targeting [PDF]

, 2014
Lalatsa, Katerina, Moreira Leite, Diana
core   +1 more source

Angiogenic Potential of Small Extracellular Vesicles Produced by Stimulated Mesenchymal Stromal Cells Under Hypoxic Conditions

Journal of Extracellular Biology, Volume 5, Issue 1, January 2026.
ABSTRACT Regenerative vascular medicine research has positioned mesenchymal stromal cells (MSCs) as a leading candidate to treat ischemic diseases. Recent studies have highlighted the emerging role of small extracellular vesicles (sEVs) produced by MSCs in their own potential.
Nada Serhal, Bertrand Brassart, Lise Nannan, Sandra Audonnet, Christine Terryn, Gaël Poitevin, Pascale Cornillet‐Lefebvre, Florine Dubuisson, Hélène Peyret, Philippe Nguyen, Claire Tournois   +10 more
wiley   +1 more source

Von Willebrand factor and JAK2V617F variant allele frequency predict thrombosis and bleeding in patients with myeloproliferative neoplasms. [PDF]

Ann Hematol
Gat A, Kazoom R, Shapira I, Shai E, Roth Jelinek B, Buchman N, Kalish Y, Arad A, Zimran E.   +8 more
europepmc   +1 more source

A De Novo Splicing Mutation of SRP72 in Bone Marrow Failure Syndrome Type 1: Case Report and Review of the Literature

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study reports a rare case of bone marrow failure syndrome type 1 (BMFS1) caused by a novel de novo splicing mutation (c.1502+1G>A) in the SRP72 gene. The 6‐year‐old patient presented with aplastic anemia and pancytopenia. Genetic analysis identified the mutation, which was absent in both parents, confirming its de novo origin.
Wang Xiangwen, Zhang Duo, Hao Wenjing, Hou Hui   +3 more
wiley   +1 more source

Sodium butyrate targets VWF to inhibit cigarette smoke extract-induced endothelial cell-macrophage crosstalk in regulating inflammatory response. [PDF]

Respir Res
Ma X, Zhou J, Yang S, Zhang Y, Zhu C, Sun Y, Miao J, Mo H.   +7 more
europepmc   +1 more source

Bernard‐Soulier Syndrome: Identification of a Novel GP1BB Variant in a Mauritanian Patient

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study identifies a new mutation of the GP1BB gene responsible for Bernard‐Soulier syndrome in a Mauritanian patient. Genetic analysis reveals a nucleotide duplication resulting in a severe platelet adhesion defect. This work highlights the importance of molecular diagnosis and therapeutic strategies to improve the management of affected patients ...
Mohamed Lemine Salem, Ektelbenina Zein, Ghaber Sidi Mohamed   +2 more
wiley   +1 more source

[Diffuse large B-cell lymphoma with acquired von Willebrand syndrome: a case report and literature review]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Wang FD, Ding BJ, Li MJ, Song XW, Hu JX, Liu L, Zhou H.   +6 more
europepmc   +1 more source

Exploration of the Pathogenic Mechanism of the Factor XIII A Subunit in a Patient With Congenital Factor XIII Deficiency

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study identifies a novel Ser414Leu variant in the F13A1 gene associated with congenital FXIII deficiency, demonstrating its potential to destabilize the protein structure. ABSTRACT Background Congenital factor XIII (FXIII) deficiency is an extremely rare autosomal recessive blood clotting disorder with an incidence of approximately one in two ...
Min Wang, Nan Wei, Tianping Chen, Aoshuang Jiang, Yinghui Zhao, Chenglin Zhu, Lijuan Zhu, Lijun Qu, Hongjun Liu   +8 more
wiley   +1 more source

A clinically applicable method for early interstitial lung disease detection in incident rheumatoid arthritis cases: integration of protein biomarkers and clinical factors. [PDF]

Ann Med
Gou X, Jiao W, Chen H, Tan Y, Fan Q, Liu H, Liu Y, Chen J.   +7 more
europepmc   +1 more source

Assessing the relation between protein phosphorylation, AlphaFold3 models, and conformational variability

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Proteins perform diverse functions critical to cellular processes. Transitions between functional states are often regulated by post‐translational modifications (PTMs) such as phosphorylation, which dynamically influence protein structure, function, folding, and interactions.
Pathmanaban Ramasamy, Jasper Zuallaert, Lennart Martens, Wim F. Vranken   +3 more
wiley   +1 more source