Results 61 to 70 of about 7,052 (205)

Refining the Sox10Dom/+ mouse model: A new breeding strategy with relevance to Hirschsprung disease genetics

Animal Models and Experimental Medicine, Volume 8, Issue 10, Page 1866-1875, October 2025.
This study optimized the breeding strategy for Sox10Dom/+ mice, enhancing research efficiency. By self‐breeding the progeny B6C3Fe‐g, resulting from the cross of B6C3Fe Sox10Dom/+ males with C57BL/6J females, it was found to have a higher number of offspring and greater survival rates compared to the B6C3Fe strain, while maintaining genetic and ...
Chaoting Lan, Jiazhang Chen, Shenwei Huang, Yide Mu, Qiuhua Wang, Xin Zhong, Ning Tang, Xinying Zhao, Jieting Lu, Yuxin Wu, Lihua Huang, Jixiao Zeng, Wei Zhong, Yu Ouyang, Qiuming He, Yan Zhang   +15 more
wiley   +1 more source

SOXE neofunctionalization and elaboration of the neural crest during chordate evolution [PDF]

, 2016
During chordate evolution, two genome-wide duplications facilitated acquisition of vertebrate traits, including emergence of neural crest cells (NCCs), in which neofunctionalization of the duplicated genes are thought to have facilitated development of ...
Bronner, ME, Cheah, KSE, Cheung, MCH, Huang, YH, Jauch, R, Tai, CP   +5 more
core   +5 more sources

Syndrome de Waardenburg

The Pan African Medical Journal, 2015
Le syndrome de Waardenburg associe une surdité à des anomalies de pigmentation. Ce syndrome est autosomique dominant à pénétrance et expressivité variable en inter et en intra familial, d'où l'intérêt du diagnostic prénatal dans les cas à risque. Le type
Mahfoudhi Madiha, Khamassi Khaled
doaj   +1 more source

Shah-Waardenburg syndrome

Formosan Journal of Surgery, 2017
Introduction: Shah-Waardenburg syndrome (SWS) is WS associated with Hirschsprung's disease. It is very rare with
Rahul Gupta, Dinesh Kumar Barolia, Ramesh Tanger, Lila Dhar Agrawal, Arun Kumar Gupta, Ram Babu Goyal   +5 more
doaj   +1 more source

YY1 regulates melanocyte development and function by cooperating with MITF. [PDF]

PLoS Genetics, 2012
Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and
Juying Li, Jun S Song, Robert J A Bell, Thanh-Nga T Tran, Rizwan Haq, Huifei Liu, Kevin T Love, Robert Langer, Daniel G Anderson, Lionel Larue, David E Fisher   +10 more
doaj   +1 more source

Genetic aspects of hearing loss in the Limpopo Province of South Africa. [PDF]

, 2010
The aetiological diagnosis of recessive non-syndromic hearing loss poses a challenge owing to marked heterogeneity and the lack of identifying clinical features.
Kabahuma, Rosemary I.
core  

Shared Lineage, Distinct Outcomes: Yap and Taz Loss Differentially Impact Schwann and Olfactory Ensheathing Cell Development Without Disrupting GnRH‐1 Migration

Glia, Volume 73, Issue 10, Page 2077-2097, October 2025.
Main Points OECs, SCs, and Mel derive from SCPs. Sox10Cre;YapHet;TazKO mice show impaired SC maturation, reduced Mel formation, fewer SCPs, OECs, and olfactory neurons, but normal GnRH‐1 neuron migration. ABSTRACT Olfactory Ensheathing Cells (OECs) are glial cells originating from the neural crest and are critical for bundling olfactory axons to the ...
Ed Zandro M. Taroc, Enrico Amato Jr., Alexis M. Semon, Nikki Dolphin, Briane Beck, Sophie Belin, Yannick Poitelon, Paolo E. Forni   +7 more
wiley   +1 more source

Cranial neural crest cell contribution to craniofacial formation, pathology, and future directions in tissue engineering [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108634/1/bdrc21075 ...
Achilleos, Ashokan, Bassett, Boutros, Burstyn-Cohen, Cooper, Creuzet, Dixon, Douarin, Douarin, Dudas, Ezaldein, Graham, Green, Hou, Hsu, Huang, Ibrahimi, Ishii, Ito, Jabs, Jones, Kaartinen, Lalani, Loeys, Matera, Minoux, Mishina, Miura, Nagashima, Noden, Papangeli, Pelaez, Perez-Alcala, Pingault, Reardon, Rinon, Rogers, Roscioli, Sanger, Santagati, Shprintzen, Simoes-Costa, Southard-Smith, Takahashi, Theveneau, Theveneau, Trainor, Wang, Winograd, Xu, Young   +51 more
core   +1 more source

Epidemiology and Surgical Management of Hirschsprung's Disease in France: A 12‐Year Retrospective Analysis (2012–2023)

Acta Paediatrica, Volume 114, Issue 10, Page 2526-2534, October 2025.
ABSTRACT Aim Hirschsprung's disease (HSCR) is a congenital disorder of the enteric nervous system, leading to functional intestinal obstruction in neonates and young children. This study aimed to assess the epidemiology and surgical management of HSCR in France over a 12‐year period using nationwide data.
Xavier Xu Wang, Wilguy Doisy, Seydou Goro, Sadek Harichane, Mathilde Rousseau, Marc Bellaiche, Camille Jung   +6 more
wiley   +1 more source

Campus Update: March 1992 v. 4, no. 2 [PDF]

, 1992
Monthly newsletter of the BU Medical ...
Boston University Medical Center
core   +1 more source