Results 91 to 100 of about 160,249 (244)

Documenting the Need for a National Paid Family and Medical Leave Program: Evidence from the 2012 FMLA Survey [PDF]

open access: yes, 2014
The United States is the only high-income country that does not mandate paid family and medical leave. Instead American workers rely on a patchwork of employer-provided benefits, private insurance, state programs, public assistance, and savings to make ...
Eileen Appelbaum, Helene Jorgensen
core  

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

open access: yesAdvanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng   +14 more
wiley   +1 more source

The U.S. Science and Engineering Workforce: Recent, Current, and Projected Employment, Wages, and Unemployment [PDF]

open access: yes, 2013
[Excerpt] As Congress develops policies and programs and makes appropriations to help address the nation’s needs for scientists and engineers, it may wish to consider past, current, and projected S&E workforce trends. In this regard, this report provides
Sargent, John F, Jr.
core   +2 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

open access: yesAdvanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed   +10 more
wiley   +1 more source

The Effect of Migrant Workers on Employment,Real Wages and Inequality The Case of Israel -1995 to 2000 [PDF]

open access: yes
This paper deals with the impact of migrant workers on the Israeli wage structure, on the chances of being unemployed or out of the labor force and on inequality in gross earnings from work.
Gottlieb, Daniel
core   +1 more source

Exploring Policy Models For Extended Time Off [PDF]

open access: yes, 2010
Whether it’s a personal health condition, the birth of a new child, or the need to address a serious health issue of an aging parent, many, if not most workers, find that at certain points in their lives, they will need an extended amount of time off ...
Boots, Shelley Waters   +1 more
core   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

Are There Opportunities to Increase Social Security Progressivity Despite Underfunding? [PDF]

open access: yes, 2008
Reviews the payroll tax, Social Security's benefit formula, and outcomes by race, gender, and earnings level, and explores why low-income and minority groups do not receive greater returns on contributions.
Gordon B. T. Mermin   +1 more
core   +2 more sources

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

open access: yesAdvanced Science, EarlyView.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou   +10 more
wiley   +1 more source

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