The Long-Run Effects of California's Paid Family Leave Act on Women's Careers and Childbearing: New Evidence from a Regression Discontinuity Design and US Tax Data<sup>†</sup>. [PDF]
Bailey M, Byker T, Patel E, Ramnath S.
europepmc +1 more source
Advanced Experiment Design Strategies for Drug Development
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
A holistic approach for quantifying the value of public health programs: social return on investment (SROI) analysis of a mobile clinic as an example. [PDF]
Kumar S, Mallett A, Olsen S, Coleman A.
europepmc +1 more source
This article establishes a Taguchi–Bayesian sampling strategy to reconstruct polymer processing–property landscape at minimal sampling cost, generically building the roadmap for materials database construction from sampling their vast design space. This sampling strategy is featured by an alternating lesson between uniformity and representativeness ...
Han Liu, Liantang Li
wiley +1 more source
Cost-Utility Analysis of Immediate Sequential and Delayed Sequential Bilateral Cataract Surgery in a Middle-Income Country. [PDF]
Nguyen CN +3 more
europepmc +1 more source
LLM‐Based Scientific Assistants for Knowledge Extraction: Which Design Choices Matter?
A comprehensive framework for optimizing Large Language Models in domain‐specific applications is introduced. The LLM Playground integrates Prompt Engineering, knowledge augmentation, and advanced reasoning strategies to enable systematic comparison of architectures and base models.
David Exler +7 more
wiley +1 more source
Current and Future Replacement and Opportunity Costs of Family Caregiving for Older Americans With and Without Dementia. [PDF]
Mudrazija S, Aranda MP.
europepmc +1 more source
Phonons‐informed machine‐learning predictive models are propitious for reproducing thermal effects in computational materials science studies. Machine learning (ML) methods have become powerful tools for predicting material properties with near first‐principles accuracy and vastly reduced computational cost.
Pol Benítez +4 more
wiley +1 more source
Can wage changes solve the labour crisis in the National Health Service? [PDF]
Zhou X +5 more
europepmc +1 more source
AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song +6 more
wiley +1 more source

