Results 61 to 70 of about 287,246 (309)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Waist Circumference predicting Cardiovascular Disease in Korean Men and Women [PDF]

, 2010
Objective: Obesity and cardiovascular disease (CVD) are closely related and have become increasingly prevalent in Korea. Asians are more prone to obesity-related co-morbidities than Caucasians, even at lower body mass index (BMI) and/or smaller waist ...
Sun Ha Jee, Sat Byul Park
core  

Considerations in establishing a post-mortem brain and tissue bank for the study of myalgic encephalomyelitis/chronic fatigue syndrome: a proposed protocol. [PDF]

, 2014
BACKGROUND: Our aim, having previously investigated through a qualitative study involving extensive discussions with experts and patients the issues involved in establishing and maintaining a disease specific brain and tissue bank for myalgic ...
Lacerda, Eliana M, Hall, Alison, Djordje Gveric, Dominic G O’Donovan, O'Donovan, Dominic G, Luis Nacul, Derek Pheby, Goldring, Kirstin, Nacul, Luis, Eliana M Lacerda, Gveric, Djordje, Alison Hall, Erinna Bowman, Bowman, Erinna, Kirstin Goldring, Pheby, Derek   +15 more
core   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

A Toolkit to assess health needs for congenital disorders in low- and middle-income countries: an instrument for public health action. [PDF]

, 2013
BACKGROUND: In 2010 the World Health Assembly called for action to improve the care and prevention of congenital disorders, noting that technical guidance would be required for this task, especially in low- and middle-income countries. Responding to this
Nacul, LC, Darlison, MW, Chowdhury, S, Burton, H, Sagoo, GS, Stewart, A, Alberg, C, Grollman, C, Hall, A, Moorthie, S, Modell, B   +10 more
core   +1 more source

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies, Elin Haf Davies, Dyfrig A. Hughes   +2 more
wiley   +1 more source

Factors associated with waist circumference in UK adults’ population [PDF]

, 2022
Introduction: Waist circumference is significantly associated metabolic disease morbidity and mortality, independent of BMI. Characteristics of dietary intakes, such as overall dietary pattern, dietary fibre and fat intake, are recognised as factors ...
Albaloul, Anwar Hamoud
core   +1 more source

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, EarlyView.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Proposed cut-off points for anthropometric and bioelectrical measures based on overweight and obesity criteria in Spanish institutionalised elderly people.

PLoS ONE, 2021
The increasing prevalence of obesity among the institutionalised elderly population and its severe consequences on health requires an early and accurate diagnosis that can be easily achieved in any clinical setting.
Jose Ramon Alvero-Cruz, Rosalia Fernandez Vazquez, Javier Martinez Blanco, Ignacio Rosety, Antonio Jesus Diaz, Miguel Angel Rosety, Manuel Rosety-Rodriguez, Francisco Javier Ordonez   +7 more
doaj   +1 more source

Association Between Waist Circumference and the Prevalence of (Pre) Hypertension Among 27,894 US Adults

Frontiers in Cardiovascular Medicine, 2021
Aims: This study aimed to investigate the association between waist circumference and the prevalence of (pre) hypertension.Methods: Cross-sectional data from the 2007–2018 National Health and Nutrition Examination Survey were analyzed.
Jin-Yu Sun, Yang Hua, Hua-Yi-Yang Zou, Qiang Qu, Yue Yuan, Guo-Zhen Sun, Wei Sun, Xiang-Qing Kong   +7 more
doaj   +1 more source