Results 41 to 50 of about 8,636,999 (167)

Quantitative signal intensity in Fluid-Attenuated Inversion Recovery and treatment effect in the WAKE-UP trial [PDF]

, 2020
Background and Purpose: Relative signal intensity of acute ischemic stroke lesions in fluid-attenuated inversion recovery (fluid-attenuated inversion recovery relative signal intensity [FLAIR-rSI]) magnetic resonance imaging is associated with time ...
Ebinger, Martin, Pedraza, Salvador, Cho, Tae-Hee, Md, Claus Z. Simonsen, Gerloff, Christian, Wouters, Anke, Galinovic, Ivana, Cho, TH, Fiebach, Jochen B., Puig, Josep, Thijs, Vincent, Fiebach, JB, Muir, KW, Nighoghossian, Norbert, Laloux, Patrice, Simonsen, CZ, Simonsen, Claus Z, London, Frédéric, Nickel, A, Simonsen, Claus Z., Lemmens, R, et al., Muir, Keith W., Fiebach, Jochen B, Nighoghossian, N, Gerloff, C, WAKE-UP (Efficacy and Safety of MRI-Based Thrombolysis inWake-Up Stroke Trial, Vandermeeren, Yves, Thomalla, Götz, Cheng, Bastian, Wouters, A, Nickel, Alina, Vanacker, Peter, Thomalla, G, Boutitie, Florent, Endres, M, Muir, Keith W, De Coene, Beatrijs, Fiehler, Jens, Lemmens, Robin, Galinovic, I, Puig, J, Pedraza, S, Thijs, V, Thomalla, G\uf6tz, Ebinger, M, Boutitie, F, Endres, Matthias, Fiehler, J, Cheng, B   +49 more
core   +1 more source

Population-based study of wake-up strokes [PDF]

Neurology, 2011
Previous studies have estimated that wake-up strokes comprise 8%to 28% of all ischemic strokes, but these studies were either small or not population-based. We sought to establish the proportion and event rate of wake-up strokes in a large population-based study and to compare patients who awoke with stroke symptoms with those who were awake at time of
J, Mackey, D, Kleindorfer, H, Sucharew, C J, Moomaw, B M, Kissela, K, Alwell, M L, Flaherty, D, Woo, P, Khatri, O, Adeoye, S, Ferioli, J C, Khoury, R, Hornung, J P, Broderick   +13 more
openaire   +2 more sources

Extent of FLAIR Hyperintense Vessels May Modify Treatment Effect of Thrombolysis: A Post hoc Analysis of the WAKE-UP Trial

Frontiers in Neurology, 2021
Background and Aims: Fluid-attenuated inversion recovery (FLAIR) hyperintense vessels (FHVs) on MRI are a radiological marker of vessel occlusion and indirect sign of collateral circulation. However, the clinical relevance is uncertain.
Anne Sophie Grosch, Anna Kufner, Anna Kufner, Anna Kufner, Florent Boutitie, Florent Boutitie, Florent Boutitie, Bastian Cheng, Martin Ebinger, Martin Ebinger, Matthias Endres, Matthias Endres, Matthias Endres, Matthias Endres, Matthias Endres, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Alina Königsberg, Robin Lemmens, Robin Lemmens, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Siemonsen, Vincent Thijs, Vincent Thijs, Anke Wouters, Anke Wouters, Anke Wouters, Christian Gerloff, Götz Thomalla, Ivana Galinovic   +33 more
doaj   +1 more source

Statistical analysis of the primary outcome in acute stroke trials [PDF]

, 2012
Common outcome scales in acute stroke trials are ordered categorical or pseudocontinuous in structure but most have been analyzed as binary measures. The use of fixed dichotomous analysis of ordered categorical outcomes after stroke (such as the modified
Lees, K.R., Saver, J.L., Howard, G., TONI, Danilo, Altman, H., Schellinger, P.D., Bland, M., Hogg, C., Bath, P.M.W., European Stroke Organisation Outcomes Working Group   +9 more
core   +1 more source

An Automatic DWI/FLAIR Mismatch Assessment of Stroke Patients

Diagnostics, 2023
DWI/FLAIR mismatch assessment for ischemic stroke patients shows promising results in determining if patients are eligible for recombinant tissue-type plasminogen activator (r-tPA) treatment.
Jacob Johansen, Cecilie Mørck Offersen, Jonathan Frederik Carlsen, Silvia Ingala, Adam Espe Hansen, Michael Bachmann Nielsen, Sune Darkner, Akshay Pai   +7 more
doaj   +1 more source

Estimates of Outcomes Up to Ten Years after Stroke: Analysis from the Prospective South London Stroke Register [PDF]

, 2011
Background: Although stroke is acknowledged as a long-term condition, population estimates of outcomes longer term are lacking. Such estimates would be useful for planning health services and developing research that might ultimately improve outcomes ...
Christopher J McKevitt, Toschke, Andre M., Peter U Heuschmann, Wolfe Charles D. A., Grieve Andy P., Anthony G Rudd, Crichton Siobhan L., Andy P. Grieve, Anthony G. Rudd, Rudd Anthony G., André M. Toschke, McKevitt Christopher J., Peter U. Heuschmann, Heuschmann, Peter U., Andy P Grieve, Siobhan L Crichton, Heuschmann Peter U., McKevitt, Christopher J., André M Toschke, Charles D. A. Wolfe, Christopher J. McKevitt, Crichton, Siobhan L., Grieve, Andy P., Siobhan L. Crichton, Wolfe, Charles D. A., Toschke André M., Rudd, Anthony G., Charles D A Wolfe   +27 more
core   +1 more source

Wake Evolution of Wing-Body Configuration from Roll-Up to Vortex Decay [PDF]

, 2012
The development of aircraft’s wake vortex from the roll-up until vortex decay is studied. An aircraft model and the surrounding flow field obtained from high-fidelity Reynolds-averaged Navier-Stokes simulation are swept through a ground-fixed ...
Misaka, Takashi, Thomas Gerz, Frank Holzäpfel, Takashi Misaka, Holzäpfel, Frank, Gerz, Thomas   +5 more
core   +1 more source

Ischemic stroke with unknown onset of symptoms: current scenario and perspectives for the future

Arquivos de Neuro-Psiquiatria, 2022
Background Stroke is a major cause of disability worldwide and a neurological emergency. Intravenous thrombolysis and mechanical thrombectomy are effective in the reperfusion of the parenchyma in distress, but the impossibility to determine the exact ...
Rônney Pinto Lopes, Vivian Dias Baptista Gagliardi, Felipe Torres Pacheco, Rubens José Gagliardi   +3 more
doaj   +1 more source

Determining Stroke Onset Time Using Quantitative MRI: High Accuracy, Sensitivity and Specificity Obtained from Magnetic Resonance Relaxation Times

Cerebrovascular Diseases Extra, 2016
Many ischaemic stroke patients are ineligible for thrombolytic therapy due to unknown onset time. Quantitative MRI (qMRI) is a potential surrogate for stroke timing.
Bryony L. McGarry, Harriet J. Rogers, Michael J. Knight, Kimmo T. Jokivarsi, Olli H.J. Gröhn, Risto A. Kauppinen   +5 more
doaj   +1 more source

Rapid eye movement (REM) sleep microarchitecture is altered in patients with wake-up ischemic stroke: A polysomnographic study

Neurobiology of Sleep and Circadian Rhythms, 2021
It is well established that certain alteration of sleep disorders occur in patients with wake-up stroke (WUS) such as sleep disordered breathing, periodic limb movements and sleep duration.
Jaidaa Mekky, Osama El-Kholy, Eman Hamdy, Akram Fawzy   +3 more
doaj   +1 more source