Results 141 to 150 of about 766,112 (308)

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Experimental study of the effect on span loading on aircraft wakes [PDF]

Measurements were made in the NASA-Ames 40- by 80-foot wind tunnel of the rolling moment induced on a following model in the wake 13.6 spans behind a subsonic transport model for a variety of trailing edge flap settings of the generator.
Ciffone, D. L., Corsiglia, V. R., Rossow, V. J.   +2 more
core   +1 more source

Linearised CFD Models for Wakes

, 2011
This report describes the development of a fast and reasonably accurate model for the prediction of energy production in oshore wind farms taking wake eects into account. The model has been implemented as a windows application called Fuga which can run in batch mode or as a graphical user interface. Fuga is brie y described.
Ott, Søren, Berg, Jacob, Nielsen, Morten; id_orcid 0000-0002-8483-164X   +2 more
openaire   +2 more sources

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

Advanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source

Evaluation of a Wake Vortex Upset Model Based on Simultaneous Measurements of Wake Velocities and Probe-Aircraft Accelerations [PDF]

Simultaneous measurements were made of the upset responses experienced and the wake velocities encountered by an instrumented Learjet probe aircraft behind a Boeing 747 vortex-generating aircraft.
Jacobsen, R. A., Short, B. J.
core   +1 more source

Learnable Diffusion Framework for Mouse V1 Neural Decoding

Advanced Science, EarlyView.
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng, Peter S. Schwendeman, Yuanfang Guan   +2 more
wiley   +1 more source

Combined Effect of ABL Profile and Rotation in Wind Turbine Wakes: New Three-Dimensional Wake Model

Energies
The combination of the atmospheric boundary layer (ABL) profile and the rotation of wind turbine wakes leads to lateral and vertical displacements of the wake center and to changes in the wake diameter, which are not taken into account by conventional ...
José A. Martinez-Trespalacios, Dimas A. Barile, John L. Millan-Gandara, Jairo Useche, Alejandro D. Otero   +4 more
doaj   +1 more source

Experimental investigation of wing fin configurations for alleviation of vortex wakes of aircraft [PDF]

A variety of fin configurations were tested on a model of the Boeing B747 in 40 by 80 foot wind tunnels. The test results confirmed that a reduction in wake rolling moment was brought about by the vortex shed by the fins so that a wide range of designs ...
Rossow, V. J.
core   +1 more source