Results 21 to 30 of about 44,206 (149)

Vigilance Effects in Resting-State fMRI

Frontiers in Neuroscience, 2020
Measures of resting-state functional magnetic resonance imaging (rsfMRI) activity have been shown to be sensitive to cognitive function and disease state.
Thomas T. Liu, Thomas T. Liu, Maryam Falahpour   +2 more
doaj   +1 more source

Positive allosteric adenosine A2A receptor modulation suppresses insomnia associated with mania- and schizophrenia-like behaviors in mice

Frontiers in Pharmacology, 2023
Background: Insomnia is associated with psychiatric illnesses such as bipolar disorder or schizophrenia. Treating insomnia improves psychotic symptoms severity, quality of life, and functional outcomes.
Yang Lin, Koustav Roy, Shuji Ioka, Rintaro Otani, Mao Amezawa, Yukiko Ishikawa, Yoan Cherasse, Mahesh K. Kaushik, Daniela Klewe-Nebenius, Li Zhou, Masashi Yanagisawa, Yo Oishi, Yo Oishi, Tsuyoshi Saitoh, Tsuyoshi Saitoh, Michael Lazarus, Michael Lazarus   +16 more
doaj   +1 more source

Roles of Microglial Phagocytosis and Inflammatory Mediators in the Pathophysiology of Sleep Disorders

Frontiers in Cellular Neuroscience, 2017
Sleep serves crucial learning and memory functions in both nervous and immune systems. Microglia are brain immune cells that actively maintain health through their crucial physiological roles exerted across the lifespan, including phagocytosis of ...
Agnes Nadjar, Agnes Nadjar, Agnes Nadjar, Henna-Kaisa M. Wigren, Marie-Eve Tremblay, Marie-Eve Tremblay   +5 more
doaj   +1 more source

The Neural Correlates of Consciousness: A Spectral Exponent Approach to Diagnosing Disorders of Consciousness

Brain Sciences
Background/Objectives: Disorder of consciousness (DoC) poses diagnostic challenges due to behavioral assessment limitations. This study evaluates the spectral exponent (SE)—a neurophysiological biomarker quantifying the decay slope of ...
Ying Zhao, Anqi Wang, Weiqiao Zhao, Nantu Hu, Steven Laureys, Haibo Di   +5 more
doaj   +1 more source

EEG Microstates Indicate Heightened Somatic Awareness in Insomnia: Toward Objective Assessment of Subjective Mental Content

Frontiers in Psychiatry, 2018
People with Insomnia Disorder (ID) not only experience abundant nocturnal mentation, but also report altered spontaneous mental content during daytime wakefulness, such as an increase in bodily experiences (heightened somatic awareness). Previous studies
Yishul Wei, Jennifer R. Ramautar, Michele A. Colombo, Michele A. Colombo, Michele A. Colombo, Bart H. W. te Lindert, Eus J. W. Van Someren, Eus J. W. Van Someren, Eus J. W. Van Someren   +8 more
doaj   +1 more source

Carbachol and Nicotine in Prefrontal Cortex Have Differential Effects on Sleep-Wake States

Frontiers in Neuroscience, 2020
The role of the brainstem cholinergic system in the regulation of sleep-wake states has been studied extensively but relatively little is known about the role of cholinergic mechanisms in prefrontal cortex in the regulation of sleep-wake states.
Anjum Parkar, Donald C. Fedrigon, Farah Alam, Giancarlo Vanini, Giancarlo Vanini, Giancarlo Vanini, George A. Mashour, George A. Mashour, George A. Mashour, Dinesh Pal, Dinesh Pal, Dinesh Pal   +11 more
doaj   +1 more source

Perception of diagnosis by family caregivers in severe brain injury patients in China

BMC Palliative Care
Objectives Surrogate decision-making by family caregivers for patients with severe brain injury is influenced by the availability and understanding of relevant information and expectations for future rehabilitation. We aimed to compare the consistency of
Yifan Yan, Meiqi Li, Jitka Annen, Wangshan Huang, Tiantian Cai, Xueying Wang, Xiaohua Hu, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

Etiology and Neuropathophysiology of Coma

Türk Nöroloji Dergisi, 2012
Awareness and wakefulness require an intact connection of the neocortex with the ascending reticular formation. Any factor disrupting these pathways is likely to cause a syndrome of unconciousness. Disorders of consciousness encompass a broad spectrum of
Aslı Kıyat Atamer, Yakup Krespi
doaj   +1 more source

Wakefulness-promoting systems: progress and thinking

Di-san junyi daxue xuebao, 2021
Wakefulness is the real presentation of life. All the time, the neural mechanism of wakefulness has been the focus of its researches. With the development of single cell labeling and detection technologies and their wide application in the field of ...
HU Zhi, XIA Jianxia
doaj   +1 more source

Homeostatic plasticity in patients with disorders of consciousness detected by combined stimulation: a study protocol

Frontiers in Neurology
BackgroundNon-invasive neuromodulation (NIN) techniques have been widely utilized in treating patients with disorders of consciousness (DoC), but their therapeutic effects have been inconsistent.
Jingwen Wang, Jingwen Wang, Fangfang Shou, Qiuyi Yu, Xulan Lu, Yuwen Wan, Yuwen Wan, Wangshan Huang, Nantu Hu, Zhenyi Jin, Xinru Shan, Steven Laureys, Steven Laureys, Haibo Di   +13 more
doaj   +1 more source