Results 61 to 70 of about 44,355 (296)

Recent advances in neural mechanism of general anesthesia induced unconsciousness: insights from optogenetics and chemogenetics

Frontiers in Pharmacology
For over 170 years, general anesthesia has played a crucial role in clinical practice, yet a comprehensive understanding of the neural mechanisms underlying the induction of unconsciousness by general anesthetics remains elusive.
Hui Gao, Hui Gao, Jingyi Wang, Rui Zhang, Tao Luo   +4 more
doaj   +1 more source

Arousal State-Dependent Alterations in Neural Activity in the Zebra Finch VTA/SNc

Frontiers in Neuroscience, 2020
Sleep-wake behaviors are important for survival and highly conserved among animal species. A growing body of evidence indicates that the midbrain dopaminergic system is associated with sleep-wake regulation in mammals.
Shin Yanagihara, Maki Ikebuchi, Chihiro Mori, Ryosuke O. Tachibana, Kazuo Okanoya, Kazuo Okanoya   +5 more
doaj   +1 more source

Reduction of interictal epileptic burden by pulsatile corticoid therapy in children with drug‐resistant epilepsy—How stable is the effect?

Epileptic Disorders, EarlyView.
Abstract Objective The systematic use of pulsatile corticosteroid therapy (PCT) in children with drug‐resistant epilepsy has been shown to reduce epileptic activity. However, it remains unclear how long this effect will last. The objective of this study was therefore to evaluate the stability of the effect of PCT by assessing the interictal epileptic ...
Katharina Schiller, Tamir Avigdor, John Thomas, Daniel Mansilla, Chifaou Abdallah, Aline Kortas, Gabriele Unterholzner, Raluca Pana, Markus Rauchenzauner, Birgit Frauscher   +9 more
wiley   +1 more source

Creativity and its link to epilepsy

Epilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

La privación de sueño no afecta la resistencia aeróbica ni la concentración de lactato en sangre de jóvenes deportistas (Sleep deprivation does not affect aerobic resistance or blood lactate concentration of young athletes)

Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación, 2019
El objetivo de este estudio fue determinar si la resistencia aeróbica y la concentración de lactato en sangre, pueden ser influenciados por la privación parcial o total del sueño en un grupo de deportistas. Se reclutaron 13 deportistas masculinos (21.8 ±
Jorge Alberto Aburto Corona, Tatiana Miranda Núñez, Alicia Bárcenas Ugalde, Roberto Espinoza Gutiérrez, Emilio Manuel Arrayales Millán   +4 more
doaj   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Rest‐activity rhythm phenotypes in adults with epilepsy and intellectual disability

Epilepsia Open, EarlyView.
Abstract Objective Rest‐activity rhythms (RARs) are perturbed in many forms of neuropsychiatric illness. In this study, we applied wrist actigraphy to describe RAR perturbations in intellectually disabled adults with epilepsy (“E + ID”), using a cross‐sectional case–control design.
Nandani Adhyapak, Grace E. Cardenas, Mark A. Abboud, Vaishnav Krishnan   +3 more
wiley   +1 more source

Orexin system and pathogenesis of sleep-wake cycle disturbances in narcolepsy

Бюллетень сибирской медицины, 2018
Sleep is the one of the most important vital functions of the body. The study of the primary mechanisms that result in disturbance of the sleep-wake cycle is a priority of modern medical science.
Yu. V. Gavrilov, K. Z. Derevtsova, H. A. Korneva   +2 more
doaj   +1 more source

Chronic thalamic recordings for idiopathic generalized epilepsy and Lennox–Gastaut syndrome: Ictal and interictal electrophysiological findings

Epilepsia Open, EarlyView.
Abstract Objective To leverage RNS® System chronic thalamic EEG recordings to compare ictal and interictal thalamic electrophysiology in idiopathic generalized epilepsy (IGE) and Lennox–Gastaut Syndrome (LGS). Methods As part of ongoing clinical trials in IGE and LGS, intracranial EEG data were acquired from the centromedian nucleus (CM) bilaterally ...
Katie L. Bullinger, Angela N. Crudele, Martha J. Morrell, Lise Johnson   +3 more
wiley   +1 more source