Results 61 to 70 of about 55,000 (288)

Perception of diagnosis by family caregivers in severe brain injury patients in China

BMC Palliative Care
Objectives Surrogate decision-making by family caregivers for patients with severe brain injury is influenced by the availability and understanding of relevant information and expectations for future rehabilitation. We aimed to compare the consistency of
Yifan Yan, Meiqi Li, Jitka Annen, Wangshan Huang, Tiantian Cai, Xueying Wang, Xiaohua Hu, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

Exploring end-of-life decision-making in China for disorders of consciousness

Annals of Medicine
Objectives We aim to investigate the ethical attitudes of the Chinese population toward withdrawal of life-sustaining treatment (WLST) in disorders of consciousness (DoC) patients.Methods A self-administered questionnaire concerning WLST was distributed ...
Meiqi Li, Benedetta Cecconi, Olivia Gosseries, Lijuan Cheng, Yifan Yan, Yan Chen, Yan Li, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Heart Rate Profiles During Exercise and Incident Parkinson's Disease

Annals of Neurology, EarlyView.
Objective To determine whether established heart rate parameters of exercise, related to cardiac autonomic function, are associated with incident Parkinson's disease, independent of both clinical and autonomic prodromal features. Methods A study of UK Biobank participants who performed a standardized bicycle exercise test (2009–2013), followed until ...
Stefan van Duijvenboden, Julia Ramírez, Job Scheurink, Sirwan K. L. Darweesh, Michele Orini, Andrew Tinker, Patricia B. Munroe, Jos Thannhauser, Luc Evers, Joanna IntHout, Pier D. Lambiase, Bastiaan R. Bloem, Aiden Doherty, Marc A. Brouwer   +13 more
wiley   +1 more source

Sub-cortical and brainstem sites associated with chemo-stimulated increases in ventilation in humans [PDF]

, 2010
We investigated the neural basis for spontaneous chemo-stimulated increases in ventilation in awake, healthy humans. Blood oxygen level dependent (BOLD) functional MRI was performed in nine healthy subjects using T2weighted echo planar imaging.
Ackland, Akopyan, Banzett, Bertrand, Bianchi, Brannan, Cavanna, Cechetto, Chamberlin, Chamberlin, Chen, Colebatch, Corfield, Corfield, Critchley, Dick, Douglas, Douglas, Douglas R. Corfield, Duvernoy, Duvernoy, Evans, Evans, Fink, Fink, Friston, Friston, Gandevia, Gaytan, Gray, Haines, Harper, Herbert, Heywood, Hugo D. Critchley, Isaev, Kevin Murphy, Kjaer, Koos, Kubin, Kumar, Lavezzi, Leanne C. McKay, Macey, McKay, McKay, McKay, Middleton, Mink, Nathan, Pattinson, Peiffer, Plum, Plum, Ramsay, Richard S.J. Frackowiak, Schmahmann, Schwarzacher, Severinghaus, Shea, Skatrud, Smith, Smith, Talairach, Wenninger, Worsley, Xu, Yokota   +67 more
core   +2 more sources

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, EarlyView.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, Manjunath S. Shet, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

Roles of Microglial Phagocytosis and Inflammatory Mediators in the Pathophysiology of Sleep Disorders

Frontiers in Cellular Neuroscience, 2017
Sleep serves crucial learning and memory functions in both nervous and immune systems. Microglia are brain immune cells that actively maintain health through their crucial physiological roles exerted across the lifespan, including phagocytosis of ...
Agnes Nadjar, Agnes Nadjar, Agnes Nadjar, Henna-Kaisa M. Wigren, Marie-Eve Tremblay, Marie-Eve Tremblay   +5 more
doaj   +1 more source

Sleep pattern disruption of flight attendants operating on the Asia–Pacific route [PDF]

, 2011
Jet lag is a common issue with flight attendants in international flights, as they have to cross several time zones back and forth, while their sleep patterns get disrupted by the legally required rest times between flights, which are normally carried
Lin, Bo, Pérezgonzález, Jose D., Qiu, Yifan   +2 more
core  

Spotlight on dream recall. The ages of dreams [PDF]

, 2018
Brain and sleep maturation covary across different stages of life. At the same time, dream generation and dream recall are intrinsically dependent on the development of neural systems.
Bartolacci, Chiara, De Gennaro, Luigi, Mangiaruga, Anastasia, Scarpelli, Serena   +3 more
core   +2 more sources

Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives

BioEssays, EarlyView.
Breathing is typically automatic, ensuring homeostasis, but it is also shaped by emotion, behavior, and volition. This review synthesizes our current understanding of the flexible neural mechanisms that enable multimodal control of breathing, emphasizing the role of pontomedullary circuits.
Nathan A. Baertsch, Elora Reily, Jonathan Sedano, Ryan S. Phillips, Joseph W. Arthurs   +4 more
wiley   +1 more source