Results 111 to 120 of about 13,427,618 (297)

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

open access: yesAdvanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou   +13 more
wiley   +1 more source

Noninvasive Detection and Subtyping of Esophageal Cancer by Circulating Cell‐Free mtDNA Fragmentomics: A Multi‐Center Validation Study

open access: yesAdvanced Science, EarlyView.
Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu   +15 more
wiley   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu   +15 more
wiley   +1 more source

Computational Approach Test using Likelihood Based Tests for the Equality of Inverse Gaussian Means

open access: yesRevstat Statistical Journal
In this study, we propose three different test procedures by plugging the Wald (W), score (S) and likelihood ratio (LR) statistics into the computational approach test (CAT) to test the equality of inverse Gaussian means when the scale parameters are ...
Gamze Güven   +2 more
doaj   +1 more source

Item - Test Alternate Title

open access: yes
Item - Test Description ...
Item - Test Creator 1   +2 more
core   +1 more source

A CT Lesion Foundation Model for Non‐Invasive Assessment of Hepatocellular Carcinoma Aggressiveness and Prediction of Recurrence Risk

open access: yesAdvanced Science, EarlyView.
A computed tomography lesion foundation model, built by sequential self‐supervised pretraining on generic and hepatocellular carcinoma‐specific lesion images, non‐invasively assesses microvascular invasion and pathological grade from contrast‐enhanced CT and stratifies postoperative recurrence risk.
Wei Xia   +9 more
wiley   +1 more source

Farmers' Preferences for Gene Editing Crops and Influencing Factors

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Gene editing (GE) is gaining momentum worldwide, but limited data on UK farmers' preferences hinders our understanding of its potential impact amid deregulation debates. Based on a survey of 200 English arable farmers, we employ a Latent Class Analysis and Multinomial Logit regressions to investigate current preferences for GE crops.
Bertolozzi‐Caredio Daniele   +1 more
wiley   +1 more source

Homogeneity Test of Ratios of Two Proportions in Stratified Bilateral and Unilateral Data

open access: yesMathematics
In paired-organ studies such as ophthalmology, otolaryngology, and rheumatology, etc., various approaches take highly correlated bilateral data into account for homogeneity tests but are less likely to focus on combined bilateral and unilateral data ...
Huipei Wang, Chang-Xing Ma
doaj   +1 more source

Comparison of Relative Informational Content of Three Section and Five Section Cash-flow Statement in Explaining Future Stock Return of Listed Companies in Tehran Securities and Exchange (TSE) [PDF]

open access: yesمطالعات تجربی حسابداری مالی, 2011
The main purpose of this research is to compare the relative informational content of operating and financing cash flows of three and five section cash flow statement in explaining future stock return.
D foroghi   +3 more
doaj  

Differentiated Impacts of EU Rural Development Measures: A Finite Mixture Evaluation of Italian Olive Farms

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper examines the relationship between participation in the EU Rural Development Program and the economic performance of Italian olive farms using a finite‐mixture model with inverse‐probability‐weighted regression adjustment. Based on 2010–2022 FADN panel data, it estimates heterogeneous treatment effects while correcting for selection ...
Francesco Caracciolo, Marilena Furno
wiley   +1 more source

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