Results 91 to 100 of about 13,427,618 (297)

Testing Linear and Nonlinear Hypotheses in a Cox Proportional Hazards Model with Errors in Covariates

open access: yesLithuanian Journal of Statistics, 2019
We investigate linear and nonlinear hypotheses testing in a Cox proportional hazards model for right-censored survival data when the covariates are subject to measurement errors. In Kukush and Chernova (2018) [Theor. Probability and Math. Statist.
Oksana Chernova, Alexander Kukush
doaj   +1 more source

Choice of library size normalization and statistical methods for differential gene expression analysis in balanced two-group comparisons for RNA-seq studies

open access: yesBMC Genomics, 2020
Background High-throughput RNA sequencing (RNA-seq) has evolved as an important analytical tool in molecular biology. Although the utility and importance of this technique have grown, uncertainties regarding the proper analysis of RNA-seq data remain. Of
Xiaohong Li   +3 more
doaj   +1 more source

Australia and New Zealand CER Agreement and Breakpoints in Bilateral Trade: An Application of the Wald-type Test [PDF]

open access: yes
This paper investigates the impact of the Australia-New Zealand Closer Economic Relations (CER) Trade Agreement on bilateral trade of each member country by using historical time series data before and after the implementation of the CER.
Jayanthakumaran, Kankesu   +1 more
core  

Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
Trogocytosis efficiency varies significantly among different tumor cells and is inversely related to their cortical stiffness; this efficiency dictates the extent of immunosuppression via upregulation of CXCL5 and Arg‐1, ultimately driving CD8+T cell exhaustion and tumor escape.
Chao Liang   +9 more
wiley   +1 more source

Testing the presence of asymmetries using Wald test.

open access: yes, 2023
Testing the presence of asymmetries using Wald test.
Farhana Arefeen Mila (14846162)   +3 more
core   +1 more source

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

open access: yesAdvanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami   +7 more
wiley   +1 more source

On Wald Type Test for Poisson Processes

open access: yes, 2019
We consider two statistical problems for inhomogeneous Poisson processes. The first one concerns the parameter estimation and the second one is about the Wald test. We develop the method of moments and One-step MLE method in parameter estimation problem and describe the asymptotic behavior of the test based on the corresponding estimators. We show that
Accrachi, E, Aïdara, C, Dabye, A
openaire   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

open access: yesAdvanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu   +11 more
wiley   +1 more source

Statistical Analysis of a Generalized Linear Model for Bilateral Correlated Data Under Donner’s Model

open access: yesAxioms
Paired data often arise in medical studies, with a correlation between responses of paired organs or parts. Under an intra-correlated model, this paper proposes a generalized linear model to investigate probable confounding factors of the individual ...
Jinlong Cheng, Zhiming Li, Keyi Mou
doaj   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian   +8 more
wiley   +1 more source

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