Results 81 to 90 of about 13,427,618 (297)
Arthritis Care &Research, EarlyView.Objective This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced at least one flare during a six‐month prospective observational study were ...
Sarah Stewart +12 more
wiley +1 more source
Diagonal and unscaled Wald-type tests in general factorial designs
Electronic Journal of Statistics, 2017 In this paper, the asymptotic and permutation testing procedures are developed in general factorial designs without assuming homoscedasticity or a particular error distribution. The one-way layout, crossed and hierarchically nested designs are contained in our general framework.
openaire +2 more sources
Advanced Materials, EarlyView.Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye +11 more
wiley +1 more source
LLM‐Integrated Human–Robot Interaction System for Microrobots
Advanced Robotics Research, EarlyView.This paper proposes an LLM‐based control framework for guiding microrobots using human natural language. This framework can convert the natural human speech into safe and executable command sets for reliable navigation in complex environments. The experimental results show high accuracy and robustness in task performance, demonstrating the potential of
Bairong Zhu, Amar Salehi, Tingting Yu
wiley +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu +10 more
wiley +1 more source
Robust Wald-Type Tests under Random Censoring with Applications to Clinical Trial Analyses
, 2017 Randomly censored survival data are frequently encountered in applied sciences including biomedical or reliability applications and clinical trial analyses. Testing the significance of statistical hypotheses is crucial in such analyses to get conclusive inference but the existing likelihood based tests, under a fully parametric model, are extremely non-
Ghosh, Abhik +2 more
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WALD TYPE TESTS WITH THE WRONG DISPERSION MATRIX
, 2021 A Wald type test with the wrong dispersion matrix is used when the dispersion matrix is not a consistent estimator of the asymptotic covariance matrixof the test statistic. One class of such tests occurs when there are k groups and it is assumed that the
Rajapaksha, Kosman Watte Gedara Dimuthu Hansana
core
Advanced Science, EarlyView.Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen +7 more
wiley +1 more source
VAR Granger Causality/Block Exogeneity Wald Test (Fisherian model).
, 2020 VAR Granger Causality/Block Exogeneity Wald Test (Fisherian model).
Ahmed Mehedi Nizam (8661468)
core +2 more sources