Results 171 to 180 of about 257,982 (300)

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask   +6 more
wiley   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci   +10 more
wiley   +1 more source

Awareness and knowledge of palliative care in Tripoli, Lebanon: A cross-sectional study in a disadvantaged population. [PDF]

open access: yesPalliat Care Soc Pract
Demachkieh F   +9 more
europepmc   +1 more source

Effective methods for increasing levels of political self‐efficacy for girls and disadvantaged students in England

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This study addresses the gap in rigorous evaluation of inclusive Citizenship Education methods in reducing gender and socioeconomic inequalities in political self‐efficacy. This article tests the effectiveness of two pedagogical approaches: counter‐narratives and think‐pair‐share.
Bryony Hoskins   +2 more
wiley   +1 more source

Occupational recognition and teachers’ retention intentions: A latent profile analysis informed by recognition theory

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Teacher retention is often explained through workload, job satisfaction and burnout, but these accounts have examined less systematically whether teachers experience their profession as socially and institutionally recognised. Drawing on recognition theory, this study examines how occupational recognition is configured across material and ...
Mengting Qian   +3 more
wiley   +1 more source

Shaping Energy Transitions: Sectoral Demand, Climate Risk Exposure, and Renewable Pathways in Sub‐Saharan Africa

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Energy is a fundamental driver of economic growth, shaping productivity, industrialization, and long‐term economic resilience. In sub‐Saharan Africa (SSA), where energy access remains uneven and infrastructure is underdeveloped, understanding sector‐specific energy demand is essential for designing sustainable energy strategies.
Michael Appiah   +3 more
wiley   +1 more source

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