Results 41 to 50 of about 248,275 (303)

A likelihood approach to diagnostic tests in clinical medicine

Revstat Statistical Journal, 2005
This paper presents a pure likelihood approach to statistical inference and its relation to diagnostic tests in clinical medicine. The standard antagonistic frequentist approaches of Fisher and Neyman–Pearson–Wald, and the Bayesian perspective are ...
Basílio de Bragança Pereira , Carlos Alberto de Bragança Pereira   +1 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Adaptive Detection of Range-distributed Targets in Weighted Generalized Inverse Gaussian Clutter

Leida xuebao
In this paper, we investigate the adaptive detection of range-distributed targets in compound-Gaussian clutter, where the texture component follows a Weighted Generalized Inverse Gaussian (WGIG) distribution.
Zhenyu XU, Weijian LIU, Xiaolong CHEN, Hui CHEN, Qinglei DU, Binbin LI, Bilei ZHOU   +6 more
doaj   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Asymptotic Results for Generalized Wald Tests [PDF]

Econometric Theory, 1987
This paper presents conditions under which a quadratic form based on a g-inverted weighting matrix converges to a chi-square distribution as the sample size goes to infinity. Subject to fairly weak underlying conditions, a necessary and sufficient condition is given for this result. The result is of interest because it is needed to establish asymptotic
openaire   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective Individuals with SLE can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the area deprivation index (ADI), and FS in a national SLE sample. Methods Data were derived from RISE, a national electronic health record‐based registry.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source

As despesas familiares com educação no Brasil e a composição de gênero do grupo de irmãos

Economia Aplicada, 2009
Estudou-se a existência de viés de gênero nas escolhas paternas em gastar recursos na educação da prole. Obteve-se uma amostra de famílias da Pesquisa de Orçamentos Familiares (POF) 2002-2003, do Instituto Brasileiro de Geografia e Estatística (IBGE ...
Sérgio Carlos de Carvalho, Ana Lúcia Kassouf   +1 more
doaj   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

Cognitive Profiles of Aging in Multiple Sclerosis

Frontiers in Aging Neuroscience, 2019
BackgroundIncreasingly favorable mortality prognosis in multiple sclerosis (MS) raises questions regarding MS-specific cognitive aging and the presence of comorbidities such as Alzheimer’s disease (AD).ObjectiveTo assess elderly with MS (EwMS) and age ...
Dejan Jakimovski, Dejan Jakimovski, Bianca Weinstock-Guttman, Shumita Roy, Michael Jaworski, Laura Hancock, Alissa Nizinski, Pavitra Srinivasan, Tom A. Fuchs, Tom A. Fuchs, Kinga Szigeti, Robert Zivadinov, Robert Zivadinov, Robert Zivadinov, Ralph H. B. Benedict   +14 more
doaj   +1 more source