Results 21 to 30 of about 2,806 (137)

The non-coding RNA landscape of plasma cell dyscrasias [PDF]

, 2020
Despite substantial advancements have been done in the understanding of the pathogenesis of plasma cell (PC) disorders, these malignancies remain hard-to-treat.
Azab, Kareem A, et al,, Morelli, Eugenio, Rocca, Roberta   +3 more
core   +1 more source

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. [PDF]

, 2017
Bruton tyrosine kinase (BTK) links the B-cell antigen receptor (BCR) and Toll-like receptors with NF-κB. The role of BTK in primary central nervous system (CNS) lymphoma (PCNSL) is unknown.
Brennan, Cameron W., Campos, Carl, Clark, Owen, Codega, Paolo, DeAngelis, Lisa M., Dogan, Ahmet, Gavrilovic, Igor T., Glass, Jon, Graeber, Thomas G., Grommes, Christian, Gutin, Philip H., Hamlin, Paul, Hatzoglou, Vaios, Hsieh, Wan-Ying, Huse, Jason T., Kaley, Thomas J., Lallana, Enrico C., Mellinghoff, Ingo K., Moskowitz, Craig H., Nichol, Donna, Nolan, Craig P., Noy, Ariela, Omuro, Antonio, Palaskas, Nicolaos, Palomba, M. Lia, Panageas, Katherine S., Pastore, Alessandro, Peak, Scott, Pentsova, Elena, Reiner, Anne S., Rohle, Dan, Rosenblum, Marc, Sauter, Craig S., Schartz, Derrek, Schultz, Nikolaus, Tabar, Viviane S., Tang, Sarah S., Thomas, Alissa A., Tsyvkin, Elina, Viale, Agnes, Wolfe, Julia, Won, Minhee   +41 more
core   +2 more sources

Immunoglobulin M (IgM) multiple myeloma versus Waldenström macroglobulinemia: diagnostic challenges and therapeutic options: two case reports

Journal of Medical Case Reports, 2020
Background Immunoglobulin M multiple myeloma and Waldenström macroglobulinemia are two different hematological diseases with the common finding of an immunoglobulin M monoclonal gammopathy of unknown significance. However, clinical characteristics of the
Simona Elba, Alessia Castellino, Roberto Soriasio, Claudia Castellino, Margherita Bonferroni, Daniele Mattei, Giuliana Strola, Daniela Drandi, Nicola Mordini, Miriam Foglietta, Davide Rapezzi, Ivana Celeghini, Mariella Grasso, Fabrizio Giordano, Giulio Fraternali Orcioni, Massimo Massaia   +15 more
doaj   +1 more source

Waldenström Macroglobulinemia in Hepatitis C: Case Report and Review of the Current Literature

Case Reports in Oncological Medicine, 2014
Background. Recent literature has associated hepatitis C virus with the development of non-Hodgkin lymphoma. Hepatitis C virus infection appears to promote lymphoproliferation, providing a plausible mechanism for a causative association; however, despite
Ryan Nipp, Aaron Mitchell, Allyson Pishko, Ara Metjian   +3 more
doaj   +1 more source

Factors Regulating Immunoglobulin Production by Normal and Disease-Associated Plasma Cells [PDF]

, 2015
mmunoglobulins are molecules produced by activated B cells and plasma cells in response to exposure to antigens. Upon antigen exposure, these molecules are secreted allowing the immune system to recognize and effectively respond to a myriad of pathogens.
Elsawa, Sherine F., Jackson, David A.
core   +3 more sources

Consensus Statement on the Management of Waldenström Macroglobulinemia Patients During the COVID-19 Pandemic

HemaSphere, 2020
. In the light of the COVID-19 pandemic, the International Workshop on Waldenström Macroglobulinemia (IWWM) Treatment Recommendations Panel felt the need to provide a consensus statement for the management of Waldenström Macroglobulinemia (WM) patients ...
Dipti Talaulikar, Ranjana H. Advani, Andrew R. Branagan, Christian Buske, Meletios A. Dimopoulos, Shirley D'Sa, Maria J. Kersten, Veronique Leblond, Monique C. Minnema, Roger G. Owen, Maria Lia Palomba, Alessandra Tedeschi, Judith Trotman, Marzia Varettoni, Josephine M. Vos, Steven P. Treon, Efstathios Kastritis, Jorge J. Castillo   +17 more
doaj   +1 more source

Concomitant lymphoplasmacytic lymphoma, multiple myeloma, and amyloidosis: A diagnostic and therapeutic challenge

Clinical Case Reports, 2022
We report a case based on simultaneous occurrence of Waldenström macroglobulinemia, myeloma and amyloidosis as a collision neoplasm. The strangeness and severity of the case presented a diagnostic and therapeutic challenge, which required individualised ...
Candela Ceballos, Cristina Alburquerque, Amaya Zabalza, Iván Quispe, Ángel Panizo, Yolanda Burguete, Ana Margarita Redondo, María Carmen Mateos   +7 more
doaj   +1 more source

Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature [PDF]

, 2023
The use of specific inhibitory drugs of intracellular signaling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenström's macroglobulinemia (WM) is a recognized risk factor for Aspergillus spp. infections.
Alessandro Bartoloni, Alessandro Maria Vannucchi, Beatrice Borchi, Filippo Bartalesi, Francesca Mariotti, Irene Capolmi, Jessica Mencarini, Luca Nassi, Riccardo Paggi, Silvia Bresci   +9 more
core   +2 more sources

Cutaneous Macroglobulinosis Presenting as Serpiginous Purpura, a Case Report and Literature Review

Clinical, Cosmetic and Investigational Dermatology, 2021
Siriorn Sukanjanapong,1 Kumutnart Chanprapaph,1 Suthinee Rutnin,1 Paisan Boonsakan,2 Sulada Pukiat3 1Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of Pathology, Faculty of Medicine,
Sukanjanapong S, Chanprapaph K, Rutnin S, Boonsakan P, Pukiat S   +4 more
doaj  

Highly sensitive MYD88L265P mutation detection by droplet digital polymerase chain reaction in Waldenström macroglobulinemia

Haematologica, 2018
We here describe a novel method for MYD88L265P mutation detection and minimal residual disease monitoring in Waldenström macroglobulinemia, by droplet digital polymerase chain reaction, in bone marrow and peripheral blood cells, as well as in circulating
Daniela Drandi, Elisa Genuardi, Irene Dogliotti, Martina Ferrante, Cristina Jiménez, Francesca Guerrini, Mariella Lo Schirico, Barbara Mantoan, Vittorio Muccio, Giuseppe Lia, Gian Maria Zaccaria, Paola Omedè, Roberto Passera, Lorella Orsucci, Giulia Benevolo, Federica Cavallo, Sara Galimberti, Ramón García Sanz, Mario Boccadoro, Marco Ladetto, Simone Ferrero   +20 more
doaj   +1 more source