Results 41 to 50 of about 2,806 (137)

Waldenstrom Macroglobulinemia: Clinical Presentation, Diagnosis, and Management in an Elderly Male [PDF]

, 2023
Waldenstrom macroglobulinemia (WM) is a rare lymphoproliferative disease that can have an ambiguous clinical presentation. A key component of the pathophysiology of WM is bone marrow infiltration, which most commonly presents as anemia. Other symptoms of
Daniel, Amy, Martin, David, Reeves, James, Semerdzhiev, Dimitar I., Shahab, Shahman, Sukpraprut-Braaten, Suporn   +5 more
core   +2 more sources

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking, Sophie J. Bernelot Moens, Marie José Kersten, Femke V. M. Mulder, Steven T. Pals, Lianne Koens, Josephine M. I. Vos   +6 more
wiley   +1 more source

Clonal identification and homology differentiate primary central nervous system lymphoma from non-central nervous system lymphoplasmacytic lymphoma: a case report

Journal of Medical Case Reports
Background Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia rarely transforms into diffuse large B-cell lymphoma, and there have been no reports of cases proving clonal identity when presenting as primary central nervous system lymphoma.
Yuko Tanaka, Nahoko Furuya, Seiichi Okabe, Seiichiro Yosizawa, Seiichiro Katagiri, Michiyo Asano, Tamiko Suguro, Mitsuru Moriyama, Akiko Yamada, Shunsuke Ohtsuki, Hiroaki Fujimoto, Daigo Akahane, Moritaka Gotoh, Maki Tanigawa, Jun Matubayashi, Shinjiro Fukami, Michihiro Kohno, Toshitaka Nagao, Naoya Nakamura, Akihiko Gotoh   +19 more
doaj   +1 more source

Macroglobulinemia de Waldenström con transformación a Linfoma del manto

Galicia Clínica, 2013
La Macroglobulinemia de Waldenström (MW) es una enfermedad infrecuente con una incidencia de tres casos por millón de habitantes al año aproximadamente1 y cuyo diagnóstico siempre plantea importantes dudas.
M. Martínez Gabarrón, J.J Castellanos Monedero, M.A. Galindo Andúgar, A. Martín Castillo   +3 more
doaj   +1 more source

Hyperviscosity and Rouleaux Formation in Waldenstrom Macroglobulinemia

Annals of Internal Medicine: Clinical Cases, 2023
Waldenstrom macroglobulinemia is a distinct lymphoproliferative disorder resulting in excess production of IgM. Excess IgM and its subsequent pentameric formation may lead to the development of rouleaux and the hyperviscosity syndrome, an oncologic ...
Ishan Kirti, Bargas Alkhzouz, Iyanu Olateju, Jeffrey Iding, Deepty Bhansali, Christopher J. Haas   +5 more
doaj   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

International Journal of Cancer, Volume 159, Issue 2, Page 410-422, 15 July 2026.
What's new? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado, Angelica Macauda, Antonio José Cabrera‐Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz‐Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero‐Fernández, Elena Cabezudo, Fernando Reyes‐Zurita, Aaron D. Norman, Ramón García‐Sanz, Gabriele Capurso, Per Hoffmann, Ulrika Pettersson‐Kymmer, Francisco Jiménez‐Romera, S. Vincent Rajkumar, Niels Weinhold, Ludmila Vodickova, Christian Langer, Angelika Stein, Abdulkadir Karismaz, Victor Moreno, Markus M. Nöthen, Karl‐Heinz Jöckel, Francesca Tavano, Joaquín Martínez‐López, Shaji K. Kumar, Juan Francisco Gutiérrez‐Bautista, Daniela Basso, Florentin Späth, Yolanda Benavente, Michelle A. T. Hildebrandt, Börge Schmidt, Tereza Sevcikova, Rui Manuel Vieira Reis, Yang Li, Miguel Ángel López‐Nevot, Mihai G. Netea, Daniele Campa, Alyssa Clay‐Gilmour, Susan L Slager, Kari Hemminki, Celine M Vachon, Asta Försti, Federico Canzian, Juan Sainz   +54 more
wiley   +1 more source

Advances in the Treatment of Monoclonal Gammopaties: The Emerging Role of Targeted Therapy in Plasma Cell Dyscrasias [PDF]

, 2010
The paradigm for the treatment of monoclonal gammopaties has dramatically changed: therapeutic options in multiple myeloma (MM) have evolved from the introduction of melphalan and prednisone in the 1960s, high-dose chemotherapy and stem cell ...
Anderson, Kenneth Carl, Blotta, Simona, Ghobrial, Irene, Malagola, Michele, Roccaro, Aldo M., Russo, Domenico, Treon, Steven P.   +6 more
core  

Cutaneous amyloidosis as the first presentation of Waldenstrom macroglobulinemia

Caspian Journal of Internal Medicine, 2020
Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs ...
Rana Rafiei, Hojat Eftekhari, Behnam Rafiee   +2 more
doaj  

Retrospective Evaluation of Dual Specialty Ports in Therapeutic Apheresis

Journal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT Dual specialty ports were evaluated for safety and efficacy in therapeutic apheresis by analyzing outcomes across 97 port placement events in 88 patients, focusing on two configurations: dual Bard PowerFlow (BP2) and a combination of Bard PowerFlow with AngioDynamics SmartPort (BP + AD).
Mugtaba Swar‐Eldahab, Barnabas Obeng‐Gyasi, Paul Haste, Matthew Krosin   +3 more
wiley   +1 more source

Consequences of the recurrent MYD88 L265P somatic mutation for B cell tolerance [PDF]

, 2014
MYD88L265P has recently been discovered as an extraordinarily frequent somatic mutation in benign monoclonal IgM gammopathy, Waldenström's macroglobulinemia, and diffuse large B cell lymphoma.
Beutler, Bruce, Goodnow, Christopher, Horikawa, Keisuke, Jeelall, Yogeshraj, Wang, James   +4 more
core   +1 more source