Results 71 to 80 of about 4,953 (173)

Comparative Analysis of Four Matrix Dilution Methods for Eliminating IgM Paraprotein Interference in Prealbumin and Uric Acid Assays: Based on Two Case Reports

Journal of Clinical Laboratory Analysis, Volume 40, Issue 9, May 2026.
IgM paraproteins can cause significant interference in prealbumin (PA) and uric acid (UA) measurements, leading to falsely abnormal results. We systematically compared four dilution methods to eliminate this interference. Dilution with the PA reagent (containing PEG) effectively restored accurate PA results.
Xiaowei Chi, Zihan Liu, Weifang Liu, Huihui Jiang, Denglu Zhang   +4 more
wiley   +1 more source

Population Pharmacokinetic Modeling and Exposure‐Response Analyses of Nemtabrutinib in Patients With Hematologic Malignancies

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Nemtabrutinib is a Bruton's tyrosine kinase (BTK) inhibitor under clinical investigation in patients with hematologic malignancies, including chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL). Nemtabrutinib plasma concentration data from 578 patients enrolled in phase 1 and 2 clinical studies, treated with doses from 5 to ...
Chiara C. Kemal, Thijs J. Zweers, Elke H. J. Krekels, Manash S. Chatterjee   +3 more
wiley   +1 more source

Serum ß2-Microglobulin lin Patients with Monoclonal Gammopathies

The International Journal of Biological Markers, 1987
Beta-2-microglobulin concentrations were determined in serum samples from 45 patients with benign and malignant monoclonal gammopathies. In the group of patients suffering from multiple myeloma or Waldenström macroglobulinemia the mean β2-microglobulin ...
Samuele Di Giovanni, Gaetano Valentini, Emma Ravazzolo, Paolo Carducci, Paolo Giallonardo, Camillo Maschio   +5 more
doaj   +1 more source

Prognostic value of MYD88/CXCR4 mutation allele fraction in Waldenström macroglobulinemia using a multiplex ddPCR assay

HemaSphere, Volume 10, Issue 6, June 2026.
Eleni Thanou, Ioannis Kollias, Eleni Kalafati, Christos Vlachos, Nefeli Mavrianou‐Koutsoukou, Ourania Theologi, Maria Sakkou, Christine Liacos, Konstantina Taouxi, Alexandra Papadimou, Katerina Chrisostomidou, Agisilaos Papadopoulos, Maria Gavriatopoulou, Evangelos Terpos, Evi Lianidou, Meletios A. Dimopoulos, Efstathios Kastritis, Athina Markou, Tina Bagratuni   +18 more
wiley   +1 more source

Machine learning enhances risk stratification and treatment failure prediction in diffuse large B‐cell lymphoma

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common lymphoma subtype worldwide. Existing prognostic models, including the National Comprehensive Cancer Network International Prognostic Index (NCCN IPI), rely on small predefined variable sets, discretized inputs, and do not incorporate longitudinal clinical histories or nonlinear ...
Mikkel Werling, Alexander D. Fuglkjær, Peter Brown, Carsten U. Niemann, Rudi Agius   +4 more
wiley   +1 more source

Zanubrutinib Combined With Rituximab in the Treatment of Bing‐Neel Syndrome: A Case Report

Clinical Case Reports
Bing‐Neel syndrome (BNS) is a rare complication of Waldenström macroglobulinemia, a condition with low incidence in clinical practice and prone to misdiagnosis.
Rongyao Zhang, Juan Chang, Yanqun Shen, Ping Hu, Lulu Zhang   +4 more
doaj   +1 more source

Fatal Non‐Hepatic Hyperammonemia Post‐Glofitamab: Ureaplasma and Genetic Susceptibility: A Case Report

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background Although primarily reported in solid organ transplant recipients and patients undergoing chimeric antigen receptor T‐cell immunotherapy (CAR‐T), non‐hepatic hyperammonemia (NHHA) is a rare but lethal complication in the broader context of post‐ chemo‐immunotherapy hematologic malignancies.
Yinshan Wu, Xiuliu Guo, Xiaoling Wang, Feng Guo   +3 more
wiley   +1 more source

Waldenström-macroglobulinaemia | Waldenström macroglobulinemia

A Waldenström-macroglobulinaemia ritka, indolens lefolyású B-sejt-eredetű lymphoproliferativ kórkép. A tumorsejtek monoklonális IgM proteint termelnek, a diagnózis a monoklonális IgM és a csontvelőt infiltráló lymphoid és lymphoplasmacytoid sejtek ...
Gergely, Lajos, Udvardy, Miklós, Simon, Zsófia, Váróczy, László, Batár, Péter, Illés, Árpád, Rejtő, László, Szász, Róbert, Telek, Béla, Miltényi, Zsófia   +9 more
core   +1 more source

IMMUNOCHEMICAL STUDIES IN A PATIENT WITH WALDEN-STROM'S MACROGLOBULINEMIA [PDF]

Acta Medica Iranica, 1978
Waldenstrom's macroglobulinemia was studied in a 46 year old Iranian male with anemia, bleeding, ecchymose and splenomegaly. The diagnosis of Macroglobulinemia was established by the presence of veryhigh level of IgM paraprotein in sera which was ...
M. Mir-Ahmadian, S. Rahbar, H. Heidery, Ga. Hajaliloo   +3 more
doaj  

A Case of Bing–Neel Syndrome Successfully Treated with Ibrutinib

Case Reports in Hematology, 2018
Bing–Neel syndrome is a rare manifestation of Waldenström macroglobulinemia characterized by lymphoplasmacytic cells’ infiltration into the central nervous system.
Daniel S. O’Neil, Mark A. Francescone, Karen Khan, Alobeid Bachir, Owen A. O’Connor, Ahmed Sawas   +5 more
doaj   +1 more source