Results 51 to 60 of about 40,420 (297)

Wall conditioning for ITER: Current experimental and modeling activities

, 2014
Wall conditioning will be required in ITER to control fuel and impurity recycling, as well as tritium (T) inventory. Analysis of conditioning cycle on the JET, with its ITER-Like Wall is presented, evidencing reduced need for wall cleaning in ITER ...
Pitts, R. A., Rohde, V., ASDEX-UpgradeTeam, Pitts, R., Lomas, P., Hong, S. H., Wauters, T., Vries, P. C., De, Kogut, D., Brezinsek, S., de Vries, P. C., Hong, S., Hagelaar, Gerjan, Hagelaar, G. J. M., Contributors, JET EFDA, Vries, P., Douai, D., Lyssoivan, A., Pitts, R.A., Lomas, P. J., Nunes, I., Hagelaar, G.   +21 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Impact Analysis of Window-Wall Ratio on Heating and Cooling Energy Consumption of Residential Buildings in Hot Summer and Cold Winter Zone in China

Journal of Engineering, 2015
In order to assess the optimal window-wall ratio and the proper glazing type in different air conditioning system operation modes of residential buildings for each orientation in three typical cities in hot summer and cold winter zone: Chongqing ...
Qiaoxia Yang, Meng Liu, Chang Shu, Daniel Mmereki, Md. Uzzal Hossain, Xiang Zhan   +5 more
doaj   +1 more source

Studies of material migration and deposition after the 2017 experimental campaign in EAST

Nuclear Materials and Energy, 2022
Plasma-wall interaction is one of the key issues in tokamaks, as the material erosion and deposition will strongly influence the lifetime of plasma facing materials, fuel retention and plasma performance.
Rong Yan, Jiao Peng, Changjun Li, Guoliang Xu, Rui Ding, Wei Zheng, Binfu Gao, Dahuan Zhu, Baoguo Wang, Lei Mu, Junling Chen, Fujun Gou, Yuwei You, Zongbiao Ye, Kun Zhang, Xiongyuan Si   +15 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Plasma performance enhancement and impurity control using a novel technique of argon–hydrogen mixture fueled glow discharge wall conditioning in the ADITYA-U tokamak

Nuclear Fusion
Effective control of impurities and precise regulation of the fueling gas are supreme prerequisites for optimal operation in any fusion device. Conventional wall-conditioning methods fall short of achieving optimal wall conditioning.
K.A. Jadeja, J. Ghosh, K.M. Patel, A.B. Patel, R.L. Tanna, Kiran Patel, B.G. Arambhadiya, K.D. Galodiya, Rohit Kumar, S. Aich, Harshita Raj, L. Pradhan, M.B. Chowdhuri, R. Manchanda, N. Ramaiya, Nandini Yadava, Sharvil Patel, Kajal Shah, Dipexa Modi, A. Gauttam, K. Singh, S. Dolui, Ankit Kumar, B. Hegde, A. Kumawat, Minsha Shah, R. Rajpal, U. Nagora, P.K. Atrey, S.K. Pathak, Shishir Purohit, A. Adhiya, Manoj Kumar, Kumudni Assudani, D. Kumavat, S.K. Jha, K.S. Shah, M.N. Makwana, Shivam Gupta, Supriya Nair, Kishore Mishra, D. Raju, P.K. Chattopadhyay, B.R. Kataria   +43 more
doaj   +1 more source

Larger infarct size but equal protection by ischemic conditioning in septum and anterior free wall of pigs with LAD occlusion

Physiological Reports, 2019
The ischemic area at risk (AAR) is one major determinant of infarct size (IS). In patients, the largest AAR is seen with a proximal occlusion of the left anterior descending (LAD) coronary artery, which serves parts of the septum and of the anterior free
Andreas Skyschally, Helene Hagelschuer, Petra Kleinbongard, Gerd Heusch   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source