Results 61 to 70 of about 292,271 (308)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Removal of fuel retention by direct-current glow discharge under strong magnetic field in EAST superconducting tokamak

Nuclear Fusion
Recent research has been conducted on the removal of retained fuel particles from the first wall surfaces in the EAST superconducting tokamak, by using direct-current Glow Discharge Cleaning (GDC) under strong magnetic field.
Hao Sun, Yaowei Yu, Bin Cao, Guizhong Zuo, Jiansheng Hu   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Wall conditioning effects of boron powder injection in KSTAR with a tungsten divertor

Nuclear Fusion
Boron powder dropped into KSTAR plasmas decreased the radiated power, core electron density, and $Z_\mathrm {eff}$ , indicating that the ablated and redeposited boron powder helped to condition the plasma-facing surfaces.
Hanna Schamis, Erik P. Gilson, Hyungho Lee, Rajesh Maingi, SangKyeun Kim, Joseph A. Snipes, SeongMoo Yang, Alessandro Bortolon, Juhyeok Jang, Boseong Kim, Dongcheol Seo, Jaein Song, Hyunmyeong Lee, the KSTAR collaboration   +13 more
doaj   +1 more source

Experimental study on metallic impurity behavior with boronization wall conditioning in EAST tokamak

Nuclear Materials and Energy
Operation of EAST tokamak with full metal wall without any wall conditioning are attempted in 2023 and 2024 experimental campaign to address the issues related to ITER tungsten wall operation. It is found that H-mode plasma could be sustained even with a
Yunxin Cheng, Ling Zhang, Ailan Hu, Shigeru Morita, Wenmin Zhang, Chengxi Zhou, Darío Mitnik, Fengling Zhang, Jiuyang Ma, Zhengwei Li, Yiming Cao, Haiqing Liu   +11 more
doaj   +1 more source

Primary amyloidoma of chest wall – a rare condition [PDF]

BMJ Case Reports, 2012
Organ specific amyloidosis has been shown to be confined to various organs like liver, lung, spleen, urinary bladder and gastro-intestinal tract, but amyloidoma or tumoural amyloidosis of chest wall with no evidence of systemic amyloidosis is an extremely rare presentation and only two cases have been reported till now.
Suresh, Kumar, Surender, Kumar, Arshad, Ahmad, Awanish, Kumar   +3 more
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Fuel recycling and impurity characteristics in long-pulse H-mode plasmas with full metal and dynamically coated walls on EAST

Nuclear Fusion
We report the basic behaviors of fuel recycling and impurity accumulation during >100 s long-pulse H-mode plasma under full metal wall conditions on EAST.
Z. Wang, Z. Sun, K. Wu, Y. Huang, W. Xu, Y.H. Guan, M. Huang, H.M. Zhang, J.J. Yang, Y.M. Duan, L. Zhang, Y.W. Yu, X.Z. Gong, G.Z. Zuo, J.S. Hu   +14 more
doaj   +1 more source

Building thermal performance, extreme heat, and climate change [PDF]

, 2017
The leading source of weather-related deaths in the United States is heat, and future projections show that the frequency, duration, and intensity of heat events will increase in the Southwest.
Chester, MV, Eisenman, D, English, P, Nahlik, MJ, Pincetl, SS, Sivaraman, D   +5 more
core   +2 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source