Results 91 to 100 of about 8,292 (286)

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

open access: yesAdvanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang   +9 more
wiley   +1 more source

The Temple of Morality: Thomas Holcroft and the Swerve of Melodrama [PDF]

open access: yes, 2003
Roll 43a. Repository (Col.Ch.) / Tre Ore (Col.Ch.). Image 12 of 59. (2 April, 1953; 3 April, 1953) [PHO 1.43a.13]The Boleslaus Lukaszewski (Father Luke) Photographs contain more than 28,000 images of Saint Louis University people, activities, and events ...
Hoeveler, Diane
core   +2 more sources

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

open access: yesAdvanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng   +10 more
wiley   +1 more source

Is laparoscopic approach for wandering spleen in children an option?

open access: yesJournal of Minimal Access Surgery, 2019
Aim: Wandering spleen present generally as an acute abdomen after twisting of the splenic vascular pedicle. This study aimed to review the literature with regard to the management and outcomes of the laparoscopy in children with wandering spleen. Methods:
Gratiana Oana Alqadi, Amulya K Saxena
doaj   +1 more source

Between the flânerie and the ostracism: the subjective resignification of the city in Fabián Casas and Martín Gambarotta [PDF]

open access: yes, 2015
Desde los estudios pioneros de Walter Benjamín dedicados a la imagen del flâneur en la poesía de Baudelaire, la experiencia del sujeto poético y su íntima reconstrucción afectiva de la ciudad constituyen un índice significativo para aproximarnos a la ...
Sosa, Carlos Hernán
core   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu   +9 more
wiley   +1 more source

Wandering spleen: Case report

open access: yesEast African Medical Journal, 2010
Wandering spleens are rare clinical entities found more commonly in women aged 20-40 years. We report one such case found in a 24-year-old nulliparous woman who presented with low abdominal pains of sudden onset and splenomegaly. An emergency abdominal CT scan showed an enlarged spleen located in the right lumbar region and extending into the pelvis ...
Mwango, G.N, Muriithi, I.M
openaire   +4 more sources

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

Wandering spleen

open access: yes, 2015
Clinical History: 74y female with a 2.2 cm enhancing left renal mass, concerning for renal cell carcinoma underwent a robotic partial nephrectomy.Postoperatively the patient developed fever, hence repeat CT abdomen was performed.
openaire   +2 more sources

Splenic duplication: a rare cause of acute upper gastrointestinal bleeding [PDF]

open access: yes, 2018
Acute gastrointestinal bleeding represents a common medical emergency. We report the rare case of acute upper gastrointestinal bleeding caused by varices in the gastric fundus secondary to splenic duplication.
Alkadhi, Hatem   +4 more
core  

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