Results 161 to 170 of about 108,453 (351)

An Oncological Emergency: Severe Type B Lactic Acidosis From Warburg Effect in Diffuse Large B-cell Lymphoma [PDF]

open access: diamond, 2022
Raghavendra Sanivarapu   +6 more
openalex   +1 more source

Hepatocyte BPGM Induces RET Lactylation and Macrophage Reprogramming to Promote Tumorigenesis in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Mechanistic schematic diagram.BPGM promotes the expression level of RET by increasing the lactylation of RET‐K549 and inhibiting its ubiquitination levels in HCC cells. Furthermore, BPGM in HCC cells could also promote M2 polarization in macrophages through lactate secretion. Both of the mechanisms could promote the progression of HCC. ABSTRACT Aerobic
Jiajia Zhang   +10 more
wiley   +1 more source

Association between individual Warburg‐related proteins and prognosis in colorectal cancer

open access: yesThe Journal of Pathology: Clinical Research
We previously showed that Warburg subtyping (low/moderate/high), based on the expression of six glycolytic proteins and transcriptional regulators [glucose transporter 1 (GLUT1), pyruvate kinase M2 (PKM2), lactate dehydrogenase A (LDHA), monocarboxylate ...
Kelly Offermans   +9 more
doaj   +1 more source

A minimal model for explaining the higher ATP production in the Warburg effect

open access: gold, 2015
Stefan Schuster   +3 more
openalex   +1 more source

Unveiling the Formation and Evolution of the Cathode–Electrolyte Interphase in Lithium–Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
By integrating electrochemical impedance spectroscopy (EIS), background‐subtracted in situ Fourier‐transform infrared (FTIR) spectroscopy, and X‐ray absorption spectroscopy (XAS), this work reveals electrolyte decomposition and the reduced species involved in forming the cathode–electrolyte interphase (CEI) in lithium–sulfur batteries (LSBs), offering ...
Murilo Machado Amaral   +9 more
wiley   +1 more source

H⁺ Exchange‐Driven ppb‐Level and High‐Selective Formaldehyde Detection at Room Temperature for Environmental and Clinical Applications

open access: yesAdvanced Science, EarlyView.
This article presents an innovative room‐temperature formaldehyde sensor based on H⁺ exchange method, achieving ppb‐level detection limit and exceptional selectivity. The study highlights its practical potential for real‐time environmental monitoring and clinical diagnostic applications.
Lubing Cai   +9 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

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