Results 161 to 170 of about 678,174 (319)

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

Advanced Science, EarlyView.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng, Yunhao Pan, Fengyuan Qian, Diya Liu, Danrong Ye, Bolin Yu, Seng Zhong, Wenfang Zheng, Xuehui Wang, Baian Zhou, Yuying Wang, Lin Fang   +11 more
wiley   +1 more source

A moment in time: from the digital record of a migrating library [PDF]

, 2005
This paper draws on the work of the Arts & Humanities Research Council-funded Glasgow Cassirer Project, which makes correspondence and documents relating to the German philosopher Ernst Cassirer (1874-1945) available online. The paper concentrates on
Whitaker, G.
core  

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

Advanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang, Zhiyuan Zheng, Shilu Zhu, Liang Xu, Qingdong Zhang, Jie Gao, Min Ye, Shuwei Shen, Jinyu Xing, Ming Wu, Ronald X. Xu   +10 more
wiley   +1 more source

Impedance of a hydrogen--fed SOFC anode: Analytical and numerical models based on the dusty gas transport model [PDF]

arXiv
Analytical low-current and numerical high--current models for the impedance of a hydrogen--fed anode of an anode--supported button SOFC are developed. The models use the dusty gas transport model for the binary H$_2$--H$_2$O mixture. We show that neglecting the pressure gradient may lead to a severe underestimation of the effective hydrogen diffusivity
arxiv  

High‐Entropy Non‐Flammable Ionic Liquid/Dimethoxymethane Composite Electrolyte for High‐Performance Lithium‐Ion Batteries

Advanced Science, EarlyView.
An ionic liquid/ether composite high‐entropy electrolyte with a unique Li+ coordination structure that leads to an upgraded solid‐electrolyte interphase and improved Li+ desolvation kinetics is developed. It exhibits high thermal stability, negligible corrosivity, and a large potential window, and is highly compatible with graphite, SiOx, and high ...
Purna Chandra Rath, Chun‐Yen Chen, Jagabandhu Patra, Chun‐Chen Yang, Yu‐Sheng Su, Chien‐Te Hsieh, Wei‐Ren Liu, Ju Li, Jeng‐Kuei Chang   +8 more
wiley   +1 more source

How germline genes promote malignancy in cancer cells

BioEssays, Volume 45, Issue 1, January 2023., 2023
We hypothesize that activation of a “germline program” promotes oncogenesis. Expression of otherwise germline specific genes may result in pseudomeiotic activity, thereby promoting oncogenesis through genomic instability. Other processes that are differentially regulated in the germline, such as migration and epigenetic – and metabolic plasticity, may ...
Jan Willem Bruggeman, Jan Koster, Ans M. M. van Pelt, Dave Speijer, Geert Hamer   +4 more
wiley   +1 more source

Nonaqueous Electrolyte Rechargeable Manganese Batteries with Potassium Manganese Hexacyanoferrate Cathodes

Advanced Science, EarlyView.
This study presents manganese batteries utilizing a MnHCF cathode using an organic electrolyte solution. The MnHCF demonstrates high performance and durability. Furthermore, the organic/inorganic SEI layers formed on the Mn metal anode are comprehensively analyzed.
Jangwook Pyun, Hyeonjun Lee, Seunghyeop Baek, Sangki Lee, Hyeju Kwon, Hyeongseok Lee, Chung‐Yul Yoo, Munseok S. Chae   +7 more
wiley   +1 more source

SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway

Advanced Science, EarlyView.
Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang, Siyuan Qin, Xiaokang Li, Ming Chang, Tianzi Wei, Xin Huang, Haibo Tong, Xia Guo, Yi Lu, Jian Zhang   +9 more
wiley   +1 more source

Poly(pentacenetetrone) as a High‐capacity Cathode for Sodium Batteries

Advanced Science, EarlyView.
Poly(pentacenetetrone) (PPT) is introduced as a high‐capacity cathode for sodium batteries, offering 314 mAh g⁻¹ at 0.2C with excellent cycling stability. At 2C, it retains 92% capacity after 500 cycles. PPT's high performance and stability address key challenges in sodium battery technology, making it a promising material for next‐generation energy ...
Chinmaya Mirle, Philipp A. Schuster, Luis Kolb, Litwin Jacob, Alexander J.C. Kuehne   +4 more
wiley   +1 more source