Results 161 to 170 of about 106,451 (346)

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

open access: yesAdvanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin   +3 more
wiley   +1 more source

Association between individual Warburg‐related proteins and prognosis in colorectal cancer

open access: yesThe Journal of Pathology: Clinical Research
We previously showed that Warburg subtyping (low/moderate/high), based on the expression of six glycolytic proteins and transcriptional regulators [glucose transporter 1 (GLUT1), pyruvate kinase M2 (PKM2), lactate dehydrogenase A (LDHA), monocarboxylate ...
Kelly Offermans   +9 more
doaj   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

open access: yesAdvanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian   +11 more
wiley   +1 more source

Microstructural Insights Into LATP Ceramic Nanofibers for High‐Performance Quasi‐Solid‐State Batteries

open access: yesAdvanced Science, EarlyView.
A sustainable electrospinning technique produces LATP ceramic nanofibers that form continuous Li⁺‐conductive pathways within composite solid electrolytes. The resulting quasi‐solid‐state batteries combine the strength of ceramic nanofibers with the flexibility of polymers, delivering high critical current density and excellent rate performance at room ...
Sivaraj Pazhaniswamy   +3 more
wiley   +1 more source

Defect‐Engineered CoSe2 Quantum Dots Exposing Highly Active (111) Facets with Lithiophilic‐Sulfurophilic Functionality for High‐Energy Lithium–Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
Defective CoSe2 QDs confined within carbon microspheres (CoSe2@C) are prepared as an advanced sulfur cathode host material. The exposure of highly active (111) facets and the abundant selenium vacancies not only provides more active sites but also accelerates the catalytic conversion dynamics and lowers the reaction energy barrier of Li–S batteries ...
Xue Li   +10 more
wiley   +1 more source

HRD1 Elicitation of An Anti-Warburg Effect by Targeting PFKP to Inhibit Breast Cancer Growth and Progression [PDF]

open access: green, 2020
Ya Fan   +7 more
openalex   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

open access: yesAdvanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi   +4 more
wiley   +1 more source

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