Results 161 to 170 of about 13,460,861 (391)

A New Target for Hepatic Fibrosis Prevention and Treatment: The Warburg Effect

open access: yesFrontiers in Bioscience-Landmark
Hepatic fibrosis is a major public health problem that endangers human wellbeing. In recent years, a number of studies have revealed the important impact of metabolic reprogramming on the occurrence and development of hepatic fibrosis.
Meng Pan, Huanyu Li, Xiaoyan Shi
doaj   +1 more source

The role of cellular oxidative stress in regulating glycolysis energy metabolism in hepatoma cells

open access: yesMolecular Cancer, 2009
Background The Warburg effect has been found in a wide spectrum of human cancers, however the underlying mechanisms are still unclear. This study aims to explore the role of cellular oxidative stress in relation to glycolysis and the Warburg effect in ...
Shi Dong-yun   +5 more
doaj   +1 more source

The Mitochondrial Warburg Effect: A Cancer Enigma

open access: yesInterdisciplinary Bio Central, 2009
"To be, or not to be?" This question is not only Hamlet`s agony but also the dilemma of mitochondria in a cancer cell. Cancer cells have a high glycolysis rate even in the presence of oxygen. This feature of cancer cells is known as the Warburg effect, named for the first scientist to observe it, Otto Warburg, who assumed that because of mitochondrial ...
Taeho Kim   +6 more
openaire   +2 more sources

Review of Multifunctional Neural Probe

open access: yesAdvanced Materials Interfaces, EarlyView.
Modern multifunctional neural probes for brain‐machine interfaces extend beyond basic electrical functions to incorporate chemical and optical modalities. This review explores recent advances in multifunctional probes developed for neural signal acquisition and stimulation, highlighting how these innovations enhance the precision of brain activity ...
Ziqi Jia, Yong Kyu Yoon
wiley   +1 more source

PKM2 promotes reductive glutamine metabolism

open access: yesCancer Biology & Medicine, 2018
Objective: Pyruvate kinases M (PKM), including the PKM1 and PKM2 isoforms, are critical factors in glucose metabolism. PKM2 promotes aerobic glycolysis, a phenomenon known as “the Warburg effect”.
Miao Liu   +7 more
doaj   +1 more source

Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors

open access: yesPLOS Computational Biology, 2018
Cancer metabolism has received renewed interest as a potential target for cancer therapy. In this study, we use a multi-scale modeling approach to interrogate the implications of three metabolic scenarios of potential clinical relevance: the Warburg effect, the reverse Warburg effect and glutamine addiction.
Mengrou Shan   +4 more
openaire   +5 more sources

Cu and Cu‐30Ni Alloy as Anti‐Viral Materials for High‐Touch Surfaces: Efficacy in a Simulated Public Environment with Frequent Cleaning Practices

open access: yesAdvanced Materials Interfaces, EarlyView.
This study evaluates the antiviral efficacy and corrosion behavior of pure copper and Cu‐30Ni alloy on high‐touch surfaces under simulated public conditions with periodic cleaning. Copper shows faster virus inactivation due to higher ion release, while Cu‐30Ni offers better aesthetic durability.
Valentin Romanovski   +10 more
wiley   +1 more source

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