Results 121 to 130 of about 76,947 (296)

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Thoughts about my first months at the Warburg Institute

, 2023
Studying manuscripts is often an adventure. The starting point is known: it is established by the studies dealing with our subject and sectorial bibliography. Although the point of arrival is well defined in our minds, it may sometimes be embellished through the power of imagination, but it always remains clear, limpid and lucid: it is indeed an ...
openaire   +2 more sources

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

Advanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han, Jinpeng Zhou, Gang Zhu, Fan Chen, Leiyang Li, Wenxing Cui, Fang Sun, Tian Feng, Yue Zhang, Qiang Wang, Shuoyao Ma, Chengxuan Guo, Ziwen Zhang, Kai Wang, Jiahui Wang, Liangbo Wang, Wencong Li, Chenyi Yuan, Haixiao Liu, Liang Wang, Yan Qu   +20 more
wiley   +1 more source

Experiments on the carboxylase of pea roots [PDF]

, 1941
It is known that vitamin B1 is a growth factor for numerous bacteria and fungi including the yeasts (see the summary in Koser and Saunders (1938)). It has also been demonstrated that vitamin B1 is essential for the growth of the isolated roots of higher ...
Heegaard, Erik, Horowitz, N. H.
core  

Synergistic Se‐Doping and Accompanying S‐Vacancies Drive Lattice Distortion and p‐Band Modulation for Enhanced Sodium Storage in Sulfides

Advanced Science, EarlyView.
Se‐doping in sulfides facilitates the creation of S vacancies. The collaboration of Se‐doping and S vacancies not only induces lattice distortion to weaken the M─S bonds and lift the p‐band center for improved Na+ adsorption, but also increases the number of charge carriers for an improved electronic conductivity.
Chunyang Xu, Jinfeng Liu, Biao Ma, Yawen Liang, Dongdong Wang, Chengcheng Miao, Jianhua Zhu, Liu Wang, Yunfeng Chao, Xinwei Cui   +9 more
wiley   +1 more source

Big pictures after Dawn: ‘ontology’ for historians and utopians

BJHS Themes
This essay approaches the history of science's ‘big pictures’ through the study of cosmograms, or concrete representations of the universe as a whole. It draws on two recent developments in anthropology: first, Graeber and Wengrow's sweeping overview of ...
John Tresch, James Poskett
doaj   +1 more source

One‐Step, High‐Removal‐Rate and Low‐Damage Chemical Mechanical Polishing of InP Enabled by Hydrolysis Activated PF6− with In Situ Fluoride Passivation

Advanced Science, EarlyView.
In this work, we propose a CMP method for InP using NH4PF₆, which hydrolyzes under In3+ catalysis to form reactive species. These convert InP into low‐binding‐energy fluorides, facilitating removal and dissolution. The process delivers high material removal rates, smooth surfaces, and fluorine passivation that lowers defect density and improves ...
Shigong Fu, Jianwei Zhou, Chenwei Wang, Yanchao Ge, Chong Luo, Yuhang Qi   +5 more
wiley   +1 more source

Bipolar Covalent Organic Frameworks Crafting Core–Shell Heterostructured Cathode for High–Performance Lithium–Organic Batteries

Advanced Science, EarlyView.
A bipolar CNT@COF core–shell heterostructure cathode constructed via synergistic molecular and microstructural engineering enables rapid electron/ion transport and efficient utilization of electroactive groups for high–performance lithium–organic batteries. ABSTRACT Covalent organic frameworks (COFs) with tunable molecular structures and ordered porous
Yalong Jiang, Nan Jiang, Yu Dou, Zixuan Chen, Yunhai Zhu, Long Chen, Yingkui Yang   +6 more
wiley   +1 more source

The work of Ernst H. Gombrich on the Aby M. Warburg fragments [PDF]

Journal of Art Historiography, 2011
On January 1, 1936, Ernst Gombrich arrived in London from Austria. His task was to reorganize the last of Warburg’s fragments and, in particular, to revise what was left of the incomplete mnemosyne atlas.
Katia Mazzucco
doaj  

Landscape History and Theory: from Subject Matter to Analytic Tool [PDF]

, 2004
This essay explores how landscape history can engage methodologically with the adjacent disciplines of art history and visual/cultural studies.
Birksted, Jan Kenneth
core