Results 111 to 120 of about 162,494 (358)

Pharmacology of heparin and warfarin

Journal of the American College of Cardiology, 1986
Thromboembolic obstruction to three major components of the circulation--arterial, venous and intravascular foreign surfaces--contributes to premature death and disability in Western society. In many, but not all, of these conditions associated with thromboembolism, heparin and warfarin are the drugs of choice. It is the purpose of this presentation to
Sanford N. Gitel, Stanford Wessler
openaire   +3 more sources

The incidence of serious complications after selective laser trabeculoplasty

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the incidence of serious complications after selective laser trabeculoplasty (SLT). Methods All patients who underwent SLT at the Department of Ophthalmology, Helsinki University Hospital, were eligible for the study from 1 January 2012 to 31 December 2018.
Eeva S. Ojanen, Joni A. Turunen, Mika Harju   +2 more
wiley   +1 more source

Warfarin and Flavonoids Do Not Share the Same Binding Region in Binding to the IIA Subdomain of Human Serum Albumin

Molecules, 2017
Human serum albumin (HSA) binds a variety of xenobiotics, including flavonoids and warfarin. The binding of another ligand to the IIA binding site on HSA can cause warfarin displacement and potentially the elevation of its free concentration in blood ...
Hrvoje Rimac, Claire Dufour, Željko Debeljak, Branka Zorc, Mirza Bojić   +4 more
doaj   +1 more source

Upper extremity deep vein thrombosis associated with systemic lupus erythematosus and antiphospholipid syndrome

Journal of General and Family Medicine, EarlyView.
Masahiro Yabe, Nozomi Ozaki, Nobuhiro Sato, Norihito Nakamura, Azusa Aoyama, Shuichi Murakami, Yasuo Hirose   +6 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Bound to bleed: How altered albumin binding may dictate warfarin treatment outcome

International Journal of Cardiology: Heart & Vasculature, 2019
Although non-vitamin-K anticoagulants are now the preferred option for stroke prevention in atrial fibrillation (AF), warfarin is still used in a significant number of patients.
Anke C. Fender, Dobromir Dobrev
doaj   +1 more source

Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes (T2D) is a highly heterogeneous disease characterised by subtypes with variations in aetiology, disease progression, and risk of complications. However, potential drug targets for these subtypes have not been explored. This study aims to investigate potential drug targets by integrating proteomics.
Jiahe Wei, Hanzhang Wu, Ningjian Wang, Jiahao Zhu, Ranjit Mohan Anjana, Aleksandr V. Sokolov, Helgi B. Schiöth, Viswanathan Mohan, Xiao Tan   +8 more
wiley   +1 more source

Ascorbic acid-induced warfarin resistance after breast cancer surgery: a case report and literature review

Frontiers in Pharmacology
Warfarin is an anticoagulant that requires INR-based dosage adjustment. Ascorbic acid may impair warfarin effectiveness according to limited literature.
Pingfa Gao, Yang Shen, Ping Wu, Wenjie Lv, Wenjie Lv   +4 more
doaj   +1 more source

Interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin [PDF]

, 1969
Robert A. O’Reilly
openalex   +1 more source

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]

, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho, Hamed I. Ali, Hukihisa Fujita, Morio Yamada   +3 more
core   +1 more source