Results 121 to 130 of about 102,210 (307)

The Association of Warfarin Dosage in Clinical Use and Pharmacogenomics

, 2007
研究背景 Warfarin是臨床上一個常用來治療及預防血液栓塞疾病的藥物。然而使用warfarin來治療有其風險存在，基本上是因為病患間的個體差異，可歸因於：基因變異、環境、疾病種類及嚴重程度所影響，而使得在劑量的調整相當重要，現在臨床上的作法是監測其國際標準凝血時間比值(INR, international normalized ratio)。為達個別化用藥的目的，我們將討論可能的影響因子。 研究方法 本研究共收集94年7月至94年10月台大醫院內科部有使用warfarin之門診病患，
吳孟霖, Wu, Meng-Lin
core  

Warfarin-related nephropathy: possible role for the warfarin pharmacogenetic profile

, 2014
Warfarin-related nephropathy (WRN) is a renal complication of warfarin treatment associated with over-anticoagulation. We describe a case of a 73-year-old man affected by chronic kidney disease, essential hypertension and atrial fibrillation treated with
CARRARO, MICHELE, Giuliano Boscutti, Mary Louise Artero, Elena Bevilacqua, Sergio Bucconi, Vittorio Di Maso   +5 more
core   +1 more source

Anticoagulant Rodenticides Contribute to a Decline in an Urban Carnivore

Animal Conservation, EarlyView.
Anticoagulant rodenticides (ARs) have been shown to negatively affect carnivores globally and are closely tied to human activity and development. We examined drivers of annual survival in bobcats persisting on a residentially developed barrier island over 16 years.
Meghan P. Keating, Catherine M. Bodinof Jachowski, Duane R. Diefenbach, James D. Jordan, Nicole M. Nemeth, Thomas R. Rainwater, Gregory K. Yarrow, David S. Jachowski   +7 more
wiley   +1 more source

Patterns of warfarin use and subsequent outcomes in atrial fibrillation in primary care practices

, 2012
Edward Ewen,1 Zugui Zhang,1 Teresa A Simon,2 Paul Kolm,1 Xianchen Liu,3,4 William S Weintraub11Christiana Care Health System, Newark, DE, USA; 2Bristol-Myers Squibb, Princeton, NJ, USA; 3Indiana University School of Medicine, Indianapolis, IN, USA ...
Liu X, Zhang Z, Simon TA, Ewen E, Weintraub WS, Kolm P   +5 more
core  

The SAMe-TT2R2 Score Predicts Warfarin Control in an Australian Population with Atrial Fibrillation

, 2019
Background: Warfarin requires regular monitoring with the time in therapeutic range (TTR), a common indicator of control and TTR > 70% is indicative of efficient anticoagulation. The SAMe-TT2R2 (sex, age, medical history, treatment, tobacco use, race)
Gemma Clark, Leong, Stephanie, Kohja, Sarah, Shailendra Anoopkumar-Dukie, Clark, Gemma, Sarah Kohja, Bernaitis, Nijole, Anoopkumar-Dukie, Shailendra, Nijole Bernaitis, Stephanie Leong   +9 more
core   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Correlation between Metabolic Parameters and Warfarin Dose in Patients with Heart Valve Replacement of Different Genotypes

Reviews in Cardiovascular Medicine
Background: Warfarin has become the first choice for anticoagulation in patients who need lifelong anticoagulation due to its clinical efficacy and low price.
Xiaowu Wang, Diancai Zhao, Jipeng Ma, Xia Wang, Jincheng Liu   +4 more
doaj   +1 more source

Ischaemic Optic Neuropathy After Cardiac Surgery: A Systematic Review and Meta‐Analysis of Incidence and Risk Factors

ANZ Journal of Surgery, EarlyView.
Across 11 observational studies comprising 6 471 577 patients, the pooled incidence of ischaemic optic neuropathy after cardiac surgery was approximately 1.5 cases per 10 000 procedures. Coronary artery disease, peripheral vascular disease and anaemia were associated with increased odds of ION, although these findings should be interpreted in the ...
Daud Mutahar, Ammar Zaka, Amitouj S. Sidhu, Shahi Goswami, Aditi Singh, Jordan Ng, Brandon Stretton, Joshua G. Kovoor, Aashray K. Gupta, Stephen Bacchi, Weng Onn Chan, Celia Chen   +11 more
wiley   +1 more source

Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore

, 2018
Background: Warfarin requires ongoing monitoring of the International Normalised Ratio (INR). This is because numerous factors influence the response, including drug interactions with commonly-prescribed medications, such as statins.
Siew Teo, Ching, Chi Keong, Chi Ching, Bernaitis, Nijole, Anoopkumar-Dukie, Shailendra, Tony Badrick, Julia Crilly, Shailendra Anoopkumar-Dukie, Crilly, Julia, Andrew Davey, Teo, Siew Chong, Badrick, Tony, Davey, Andrew K, Nijole Bernaitis   +13 more
core   +1 more source

Pulmonary Embolism—A Century of Progress

ANZ Journal of Surgery, EarlyView.
Reviews a century of progress in the diagnosis, prevention, and management of pulmonary embolism; from the first successful surgical embolectomy in 1924 to advanced imaging, pharmacological thromboprophylaxis, and treatment. In the 21st century, advances include catheter‐directed thrombolysis or mechanical thrombectomy under decision‐making guidance of
D. A. Watters
wiley   +1 more source