Results 121 to 130 of about 162,494 (358)

Warfarin-related nephropathy [PDF]

open access: yesKidney International, 2012
To the Editor: In the July (2) 2011 issue, Brodsky et al.1 purport to demonstrate the consequences of warfarin-related nephropathy (WRN) among a retrospective cohort from the Ohio State University Medical Center. The cohort selection procedure was designed to yield cases of ‘presumptive’ WRN, but may have resulted in selection bias: patients who had a ...
openaire   +3 more sources

Association between CMR‐derived hepatic T1‐time, tricuspid regurgitation and survival

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
We investigated the association between tricuspid regurgitation (TR) severity and hepatic T1‐time in 1029 patients undergoing cardiac MRI and echocardiography. Hepatic T1‐time increased progressively with TR severity and remained independently associated after adjusting for NT‐proBNP and right ventricular function. Both TR and hepatic T1‐time predicted
Katharina Mascherbauer   +19 more
wiley   +1 more source

Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani   +2 more
wiley   +1 more source

Graves’ Disease and Treatment Effects on Warfarin Anticoagulation

open access: yesCase Reports in Medicine, 2014
Background. Hyperthyroidism causes an increased hypoprothrombinemic response to warfarin anticoagulation. Previous studies have demonstrated that patients with hyperthyroidism require lower dosages of warfarin to achieve a therapeutic effect.
Amanda Howard-Thompson   +4 more
doaj   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Alternative therapy interaction with warfarin: what doctors should know

open access: yesКардиоваскулярная терапия и профилактика, 2010
Warfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal ...
T. B. Kozlova   +3 more
doaj  

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

ANALYSIS OF STRUCTURAL FEATURES OF THE KETO-KETAL ISOMERS OF WARFARIN BY SPECTRAL METHODS

open access: yesРазработка и регистрация лекарственных средств, 2019
As a result of the studies was shown that the relative ratios of isomers by integration in DMSO-d6: (S, R)-warfarin – (S, S)-warfarin – open chain warfarin are 70%: 28%: 2%; in СDCl3 are 45%: 40%: 15%.
A. Z. Abyshev   +2 more
doaj  

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