Results 161 to 170 of about 192,309 (409)
British medical journal, 2015 Objective To determine the real world risk of gastrointestinal bleeding associated with the use of the novel oral anticoagulants dabigatran and rivaroxaban compared with warfarin. Design Retrospective, propensity matched cohort study. Setting: Optum Labs
N. Abraham +6 more
semanticscholar +1 more source
Calcific uraemic arteriolopathy - A mini-review [PDF]
, 2016 Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA
Agapii, Rodica +7 more
core
XANTUS: rationale and design of a noninterventional study of rivaroxaban for the prevention of stroke in patients with atrial fibrillation. [PDF]
, 2014 Atrial fibrillation (AF) is associated with a fivefold increase in the risk of stroke. The Phase III ROCKET AF (Rivaroxaban Once-Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in ...
Amarenco, P +6 more
core +2 more sources
Journal of Clinical Laboratory Analysis, EarlyView.Serum DCP may serve as an optimal biomarker for the diagnosis of HCC, but its accuracy appears to be influenced by liver function. The serum DCP may also serve as a biomarker for liver resection and interventional therapy of HCC, but is not promising for systemic treatment. ABSTRACT Background This retrospective multicenter study is aimed at evaluating
Hongying Bu +12 more
wiley +1 more source
British medical journal, 2016 Objective To determine whether the treatment effect of apixaban versus warfarin differs with increasing numbers of concomitant drugs used by patients with atrial fibrillation. Design Post hoc analysis performed in 2015 of results from ARISTOTLE (apixaban
J. Jaspers Focks +12 more
semanticscholar +1 more source
Non-valvular atrial fibrillation and stroke : implications for management [PDF]
, 1995 Nonvalvular Atrial Fibrillation is more prevalent with increasing age. It is associated with a six-fold excess risk of stroke; and a cumulative lifetime stroke risk of 35%. 15% of ischaemic strokes are directly attributable to it.
Tilney, Myra Kay
core
The Journal of Clinical Pharmacology, EarlyView.Abstract Clinical pharmacology studies are critical for determining the efficacy and safety of drugs. Due to the resource‐intensive nature of these studies, most have been conducted in high‐income countries, leading to a significant gap in clinical pharmacology data for patients in low‐ and middle‐income countries.
Aniek Uittenboogaard +7 more
wiley +1 more source
Renal function decline in Asian patients with atrial fibrillation with warfarin and non-vitamin K antagonist oral anticoagulants: A report from the COOL-AF registry. [PDF]
J ArrhythmPatients with nonvalvular atrial fibrillation (AF) from a prospective multicenter national AF registry in Thailand were studied. The objective of this study was to compare the risk of estimated glomerular filtration rate (eGFR) decline between AF patients with direct oral anticoagulants (DOACs) and warfarin.
Krittayaphong R +3 more
europepmc +2 more sources
Detection of Gene-Gene Interactions by Multistage Sparse and Low-Rank Regression [PDF]
arXiv, 2013 A daunting challenge faced by modern biological sciences is finding an efficient and computationally feasible approach to deal with the curse of high dimensionality. The problem becomes even more severe when the research focus is on interactions. To improve the performance, we propose a low-rank interaction model, where the interaction effects are ...
arxiv
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017 Background The original non–vitamin K antagonist oral anticoagulant (NOAC) trials in nonvalvular atrial fibrillation (AF) enrolled patients with native valve pathologies.
K. Pan +5 more
semanticscholar +1 more source