Results 171 to 180 of about 192,309 (409)
Pharmacology of heparin and warfarin
Journal of the American College of Cardiology, 1986 Thromboembolic obstruction to three major components of the circulation--arterial, venous and intravascular foreign surfaces--contributes to premature death and disability in Western society. In many, but not all, of these conditions associated with thromboembolism, heparin and warfarin are the drugs of choice. It is the purpose of this presentation to
Sanford N. Gitel, Stanford Wessler
openaire +3 more sources
Policy Evaluation and Optimization with Continuous Treatments [PDF]
arXiv, 2018 We study the problem of policy evaluation and learning from batched contextual bandit data when treatments are continuous, going beyond previous work on discrete treatments. Previous work for discrete treatment/action spaces focuses on inverse probability weighting (IPW) and doubly robust (DR) methods that use a rejection sampling approach for ...
arxiv
Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.Abstract Purpose Germany has high rates of total joint arthroplasty for osteoarthritis of the knee and hip. Ambulatory health interventions can affect the progression of these conditions and the need for total joint arthroplasty. Quality indicators and guideline recommendations facilitate the transparent measurement and demonstration of care quality ...
Tobias Bock +5 more
wiley +1 more source
Online Learning and Decision-Making under Generalized Linear Model with High-Dimensional Data [PDF]
arXiv, 2018 We propose a minimax concave penalized multi-armed bandit algorithm under generalized linear model (G-MCP-Bandit) for a decision-maker facing high-dimensional data in an online learning and decision-making process. We demonstrate that the G-MCP-Bandit algorithm asymptotically achieves the optimal cumulative regret in the sample size dimension T , O(log
arxiv
Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism
Journal of Thrombosis and Thrombolysis, 2016 Venous thromboembolism (VTE) is a serious and often fatal medical condition with an increasing incidence. The treatment of VTE is undergoing tremendous changes with the introduction of the new direct oral anticoagulants and clinicians need to understand ...
D. Witt +4 more
semanticscholar +1 more source
Warfarin-related nephropathy [PDF]
Kidney International, 2012 To the Editor: In the July (2) 2011 issue, Brodsky et al.1 purport to demonstrate the consequences of warfarin-related nephropathy (WRN) among a retrospective cohort from the Ohio State University Medical Center. The cohort selection procedure was designed to yield cases of ‘presumptive’ WRN, but may have resulted in selection bias: patients who had a ...
openaire +3 more sources
Cyclical medication management interventions in health care settings: A systematic review
Learning Health Systems, EarlyView.Abstract Introduction It is estimated that one in 30 patients experiences at least one preventable medication‐related harm while receiving care. Cyclical medicine improvement interventions, where health systems continuously collect data, implement prescribing/dispensing interventions, review outcomes, and revise the intervention, have demonstrated ...
Isabelle Meulenbroeks +6 more
wiley +1 more source
Influence of andrographolide on the pharmacokinetics of warfarin in rats
Pharmaceutical Biology, 2018 Context: Andrographolide and warfarin are often used together in clinics in China. However, the herb-drug interaction between andrographolide and warfarin is still unknown.
Xiaoli Zhang +3 more
doaj +1 more source
Molecules, 2017 Human serum albumin (HSA) binds a variety of xenobiotics, including flavonoids and warfarin. The binding of another ligand to the IIA binding site on HSA can cause warfarin displacement and potentially the elevation of its free concentration in blood ...
Hrvoje Rimac +4 more
doaj +1 more source