Results 41 to 50 of about 192,309 (409)
Journal of Separation Science, Volume 45, Issue 23, Page 4176-4186, December 2022., 2022 High‐performance affinity microcolumns were used to characterize binding by the anti‐diabetic drugs repaglinide and nateglinide with normal and glycated forms of human serum albumin. The microcolumns contained only nmol amounts of protein and provided a detailed analysis of these drug interactions with good precision and in a matter of minutes per ...
Susan T. Ovbude +3 more
wiley +1 more source
Enzyme polymorphism in warfarin dose management after pediatric cardiac surgery
Research in Cardiovascular Medicine, 2015 Background: Warfarin is an anticoagulant and is widely used for the prevention of thromboembolic events. Genetic variants of the enzymes that metabolize warfarin, i.e.
Avisa Tabib +4 more
doaj +1 more source
Scientific Reports, 2023 As warfarin has a narrow therapeutic window and obvious response variability among individuals, it is difficult to rapidly determine personalized warfarin dosage.
Heejung Choi +16 more
doaj +1 more source
INTERACTIONS OF WARFARIN [PDF]
Biomedical Papers, 2001 In this article, the author reviews and updates the basis of interactions with warfarin, illustrated with appropriate examples. The interactions with drugs, medicinal herbs and foods are summarised.
openaire +3 more sources
High clearance of (S)‐warfarin in a warfarin‐resistant subject. [PDF]
British Journal of Clinical Pharmacology, 1993 A 30 year old black male required a 60 mg daily dose of warfarin to elicit a therapeutic anticoagulant response (normal warfarin dose 2.5‐ 10 mg day‐1; maximum 15 mg day‐1). Hereditary warfarin resistance was suspected after compliance, diet, concurrent medication and any gastrointestinal disorder were eliminated as contributory causes. The disposition
AA Trowbridge +6 more
openaire +3 more sources
Scientific Reports, 2017 Recent global deregulation of ginseng as the table food raises our concern about the possible ginseng-warfarin interaction that could be life-threatening to patients who take warfarin for preventing fatal strokes and thromboembolism while using ginseng ...
Haiyan Dong +8 more
doaj +1 more source
Pharmaceutics, 2021 At present, the risk of generic substitutions in warfarin tablets is still being discussed. The aim of this study was to assess whether API interactions with commonly used excipients may affect the safety of generic replacement of warfarin sodium tablets.
Jan Muselík +9 more
doaj +1 more source
Clinical pharmacology and therapy, 2017 This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing.
Julie A. Johnson +15 more
semanticscholar +1 more source
Relative effects of different non-vitamin K antagonist oral anticoagulants on global thrombotic status in atrial fibrillation [PDF]
, 2016 This is an Accepted Manuscript of an article published by Taylor & Francis GroupNon-vitamin K antagonist oral anticoagulants (NOACs) reduce the risk of thromboembolism in patients with atrial fibrillation (AF).
Artman, Benjamin +8 more
core +1 more source
Warfarin Pharmacogenetics [PDF]
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2008 Significant interest in the pharmacogenetics of warfarin therapy has been triggered with the recent package insert update that highlights the potential role of pharmacogenetics in improving the safety and effectiveness of warfarin. We review the evidence of the influence of the two key genes of interest, the cytochrome P450 2C9 gene, CYP2C9, and the ...
Nita A, Limdi, David L, Veenstra
openaire +2 more sources