Results 21 to 30 of about 94,071 (310)

Warfarin Sodium Stability in Oral Formulations

Molecules, 2021
Warfarin sodium is a low-dose pharmaceutical blood thinner that exists in two forms: the clathrate form and the amorphous form. In commercially available warfarin sodium oral suspension, the active pharmaceutical ingredient (API) is added in the ...
Evangelia Dimitrokalli, Stefani Fertaki, Michail Lykouras, Petros Kokkinos, Malvina Orkoula, Christos Kontoyannis   +5 more
doaj   +1 more source

The Active Metabolite of Warfarin (3'-Hydroxywarfarin) and Correlation with INR, Warfarin and Drug Weekly Dosage in Patients under Oral Anticoagulant Therapy: A Pharmacogenetics Study. [PDF]

PLoS ONE, 2016
Warfarin oral anticoagulant therapy (OAT) requires regular and frequent drug adjustment monitored by INR. Interindividual variability, drug and diet interferences, and genetics (VKORC1 and CYP2C9) make the maintenance/reaching of stable INR a not so easy
Donato Gemmati, Francesco Burini, Anna Talarico, Matteo Fabbri, Cesare Bertocco, Marco Vigliano, Stefano Moratelli, Antonio Cuneo, Maria Luisa Serino, Francesco Maria Avato, Veronica Tisato, Rosa Maria Gaudio   +11 more
doaj   +1 more source

Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC

, 2011
Background: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset.
Förch, Christian, Waltraud Pfeilschifter, Daniel Spitzer, Pfeilschifter, Josef (Prof. Dr.), Helmuth Steinmetz, Spitzer, Daniel, Steinmetz, Helmuth, Steinmetz Helmuth, Christian Foerch, Pfeilschifter, Waltraud, Josef Pfeilschifter, Pfeilschifter Waltraud, Spitzer Daniel, Foerch Christian, Pfeilschifter Josef   +14 more
core   +1 more source

One Rare Warfarin Resistance Case and Possible Mechanism Exploration

Pharmacogenomics and Personalized Medicine, 2023
Li Zhao,1 Zhenguo Zhai,2 Pengmei Li1 1Pharmacy Department, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, People’s Republic of ...
Zhao L, Zhai Z, Li P
doaj  

A warfarin terápia és genetikai háttere

, 2021
Sajnos még a 21. században is problémába ütközik a fokozott véralvadással járó betegségek vagy állapotok, mint a tromboembólia, a mélyvénás trombózis, a szívinfarktus, a pitvarfibrilláció kezelése a lehetséges mellékhatások miatt.
Dajka, Vivien
core  

Utility of TTR-INR guided warfarin adjustment protocol to improve time in therapeutic range in patients with atrial fibrillation receiving warfarin

Scientific Reports
Warfarin remains the most prescribed oral anticoagulant of choice in atrial fibrillation (AF) patient in resource-limited settings. Despite evidence linking Time in Therapeutic Range (TTR) to patient outcomes, its use in clinical practice is not ...
Paisit Kosum, Noppachai Siranart, Kunathip Nissaipan, Wattakorn Laohapiboolrattana, Walit Sowalertrat, Kanittha Triamamornwooth, Rawiwan Arunphan, Apiradee Sriyom, Voravut Rungpradubvong   +8 more
doaj   +1 more source

Patterns of warfarin use in subgroups of patients with atrial fibrillation: a cross-sectional analysis of 430 general practices in the United Kingdom.

PLoS ONE, 2013
BackgroundDespite the proven efficacy of warfarin, its use in patients with Atrial Fibrillation (AF) is reportedly low. We investigated the underuse and overuse of warfarin in the management of AF in general practices in the United Kingdom (UK) against ...
Mohammed A Mohammed, Tom Marshall, Krishnarajah Nirantharakumar, Andrew Stevens, David Fitzmaurice   +4 more
doaj   +1 more source

XANTUS: rationale and design of a noninterventional study of rivaroxaban for the prevention of stroke in patients with atrial fibrillation [PDF]

, 2014
A John Camm,1 Pierre Amarenco,2 Sylvia Haas,3 Susanne Hess,4 Paulus Kirchhof,5,6 Martin van Eickels,4 Alexander GG Turpie71Division of Clinical Sciences, St George's, University of London, London, UK; 2Department of Neurology and Stroke Center, Paris-
Hess, S, Camm, AJ, Amarenco, Pierre, Eickels MV, Turpie, AG, Hess, Susanne, Haas, S, Turpie, Alexander G G, Kirchhof, P, van Eickels, M, Haas, Sylvia, Kirchhof, Paulus; id_orcid, Amarenco, P, Camm AJ, Hess S, Camm, John, Amarenco P, Van Eickels, Martin, Turpie AGG, Kirchhof P, Haas S   +20 more
core   +1 more source

Warfarin-Associated Fetal Subdural Hematoma Causing Severe Neurodevelopmental Delay: A Case Report

, 2023
Fetal subdural hematoma is an antenatal finding associated with significant morbidity and mortality. It can occur due to maternal or fetal risk factors, and its management varies based on the underlying cause and the anticipated long-term outcomes.
Ibrahim Safra (17993833), Ashraf Gad (17040114), Shaikha Jabor Alnaimi (17993836), Shaikha Jabor Alnaimi, Ibrahim Safra, Ashraf Gad   +5 more
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source