Results 41 to 50 of about 104,562 (257)

Analysis of queries in an HIV drug–drug interaction checker to explore changes in prescribing patterns: A 5‐year analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Careful consideration of drug–drug interactions (DDIs) is critical as people with HIV age. We analysed queries submitted to the University of Liverpool HIV Drug Interactions Database to assess changes in prescribing patterns over 5 years. Methods Queries submitted between January 2020 and December 2024 were extracted and categorized by year ...
Cecile Gras, Minh P. Le, Justin Chiong, Sara Gibbons, Daniel Seddon, Catia Marzolini, Saye Khoo   +6 more
wiley   +1 more source

EFFECTS OF DIFFERENT WARFARIN DOSES ON IL-6 AND COX-2 LEVELS

Pakistan Armed Forces Medical Journal, 2016
Background: Warfarin has been widely used for a long time as an oral anticoagulant agent. Warfarin is reported to have inflammatory role as well. The dose of Warfarin plays an important role in up and down regulation of interacting cytokines such as IL ...
Huma Shafiq, Amir Rashid, Asifa Majeed
doaj   +2 more sources

Current strategies of anticoagulation therapy for patients with non-valvular atrial fibrillation

Journal of Arrhythmia, 2012
Cardioembolic stroke accounts for 20–30% of acute brain infarctions in Japan. This condition is often severe and has poor outcomes. Non-valvular atrial fibrillation (NVAF) is the most common cardiac source of emboli in cardioembolic stroke ...
Masahiro Yasaka
doaj   +1 more source

A Large Retrospective Study to Evaluate Utility of Zephyr Covered Stent in Transcatheter Closure of Sinus Venosus Defects

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter closure (TCC) of sinus venosus defects (SVD) using balloon‐expandable covered stents is an emerging alternative to surgery. ZephyrCS (Sahajanand Laser Technologies, Gandhinagar, India) is available in long lengths to suit SVD closure.
Pramod Sagar, Puthiyedath Thejaswi, Kothandam Sivakumar, Praveen Ashok Kumar   +3 more
wiley   +1 more source

Spontaneous abdominal hemorrhage due to warfarin treatment

CHRISMED Journal of Health and Research, 2016
Warfarin is an anticoagulant used in the prevention of thromboembolism. Common clinical indications for warfarin use are atrial fibrillation, artificial heart valves, deep venous thrombosis. Common side effect of warfarin is hemorrhage.
Mustafa Volkan Demir, Tuba Öztürk Demir, Selcuk Yaylaci, Ahmet Bilal Genc   +3 more
doaj   +1 more source

One‐Year Clinical Outcomes of Paclitaxel‐Coated Balloon Angioplasty in Patients With and Without Acute Coronary Syndrome: The ALLIANCE Registry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Real‐world data after percutaneous coronary intervention (PCI) using drug‐coated balloons (DCBs) in acute coronary syndrome (ACS) are limited. Aims We compared 1‐year clinical outcomes after PCI with paclitaxel DCBs between the ACS and non‐ACS patients.
Takashi Muramatsu, Kengo Tanabe, Kazushige Kadota, Yutaka Tadano, Kenji Ando, Shigeru Nakamura, Takashi Ashikaga, Yoshihisa Kinoshita, Nehiro Kuriyama, Yuko Ohnishi, Toru Kataoka, Koji Nishida, Raisuke Iijima, Masatsugu Nozoe, Kunio Morishige, Takefumi Takahashi, Yoshitaka Murakami, Ken Kozuma, Masato Nakamura   +18 more
wiley   +1 more source

A Model for Estimating the Risk of Gastrointestinal Bleeding for Patients on Oral Anticoagulants and Interacting Medications. [PDF]

Pharmacotherapy
ABSTRACT Introduction Pharmacodynamic drug–drug interactions (DDI) in patients receiving oral anticoagulants (OAC) may increase the risk of gastrointestinal bleeding (GIB). The purpose of this study was to develop and validate a GIB model for patients receiving OACs.
Gomez-Lumbreras A, Tawfik AG, Reese T, Witt DM, Del Fiol G, Malone DC.   +5 more
europepmc   +2 more sources

A Trans‐1,2‐Diphenyl‐Substituted EDTA Platform for High‐Relaxivity Mn(II) MRI Probes

Chemistry – A European Journal, EarlyView.
Symmetric diphenyl substitution of the EDTA backbone enhances the rigidity of the Mn(II) complex and enables strong multisite interactions, providing a versatile platform for further functionalisation and conjugation towards high‐performance Mn(II)‐based MRI contrast agents.
Federico Forgione, Alessandro Nucera, Marco Ricci, Attila Benyei, Mariangela Boccalon, Zsolt Baranyai, Giovanni B. Giovenzana, Mauro Botta   +7 more
wiley   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Clinical Application of Pharmacogenetic-Based Warfarin-Dosing Algorithm in Patients of Han Nationality after Rheumatic Valve Replacement: A Randomized and Controlled Trial

International Journal of Medical Sciences, 2012
Background The polymorphisms of VKORC1 and CYP2C9 play increasingly important roles in the inter-individual variability in warfarin dose. This study aimed to evaluate the feasibility of clinical application of pharmacogenetic-based warfarin-dosing ...
MingSong Wang, XiLong Lang, ShiTao Cui, Ke Fei, LiangJian Zou, Jia Cao, LiangXu Wang, ShengHui Zhang, XinTian Wu, YiLing Wang, Qiang Ji
doaj