An Atypical Case of Warfarin-Induced Skin Necrosis [PDF]
Clinical Practice and Cases in Emergency Medicine, 2017 Skin necrosis is a relatively rare, potentially fatal side effect of warfarin. It is most commonly reported within 10 days of initiation of therapy in warfarin-naïve patients.
Lindsay R. Sklar, Anne Messman
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Warfarin Resistance: A Case Report [PDF]
Eurasian Journal of Emergency Medicine, 2019 Warfarin is the most widely prescribed anticoagulant in the world. Patients who need more than 15 mg per day should be considered warfarin-resistant.
Uğur Gönlügür +3 more
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INVESTIGATING THE GENETIC EFFECT OF VKORC1 GENE POLYMORPHISM ON WARFARIN RESPONSE IN EGYPTIAN HEART PATIENTS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2023 Warfarin is a common oral anticoagulant, but the dose needed for each patient can vary by as much as 20 times due to both environmental and genetic factors.
Hassan Donkol +4 more
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The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin. [PDF]
Clin Pharmacol TherDicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Shaul C +5 more
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Scientific Reports, 2023 As warfarin has a narrow therapeutic window and obvious response variability among individuals, it is difficult to rapidly determine personalized warfarin dosage.
Heejung Choi +16 more
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A Case Of Late-onset Warfarin Induced Skin Necrosis Resulting In Mortality
Hitit Medical Journal, 2023 Warfarin-induced skin necrosis is a rare complication of warfarin therapy and is associated with high mortality. Here, we present a case of warfarin-induced skin necrosis, that was fatal in a 53-year-old female patient who was started on warfarin ...
Pınar Korkmaz, Sinem Bayrakçı
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Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC [PDF]
, 2011 Background: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset.
Förch, Christian +14 more
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Mekanik Kalp Kapaklı Hastalarda Antikoagülan Kullanımı ve Warfarin Direnci
Ankara Medical Journal, 2015 Amaç: Mekanik kalp kapağı olan hastalarda warfarin direnci olanlar tespit edildi ve bu hastalarda uygulanan tedavi seçenekleri değerlendirildi.Materyal ve Metot: Çalışmaya 2006-2014 yılları arasında ınr takipleri yapılan mekanik kalp kapağı takılmış 40 ...
Ergun Salman +3 more
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Drug interactions between ALK inhibitors and warfarin with concurrent use of bucolome: a case report
Journal of Pharmaceutical Health Care and Sciences, 2023 Background Alectinib, crizotinib, and ceritinib, are anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) that exhibit high protein binding, and their metabolism is associated with the cytochrome P450 (CYP) isoenzymes 2C9 or 3A4.
Takashi Kato +10 more
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Use of warfarin in long-term care: a systematic review
BMC Geriatrics, 2012 Background The use of warfarin in older patients requires special consideration because of concerns with comorbidities, interacting medications, and the risk of bleeding.
Neidecker Marjorie +3 more
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