Results 81 to 90 of about 145,467 (273)

New oral anticoagulants and their reversal agents [PDF]

open access: yes, 2018
Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients\u27 quality of life, not only due to the standard ...
Bodean, Oana   +9 more
core   +1 more source

Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) [PDF]

open access: yes, 2011
<p>Background: Venous thromboembolic events (VTE), including deep venous thrombosis and pulmonary embolism, are common in older age. It has been suggested that statins might reduce the risk of VTE however positive results from studies of middle ...
A Gaw   +43 more
core   +4 more sources

Safety and effectiveness of apixaban compared to warfarin in dialysis patients

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2018
Essentials The safety of apixaban in patients on dialysis is currently debated. Bleeding events were retrospectively compared for dialysis patients on warfarin vs apixaban.
D. Reed   +5 more
semanticscholar   +1 more source

Real‐World Edoxaban Concentrations in Older Patients Receiving Reduced‐Dose Regimens

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world edoxaban concentrations in older patients receiving reduced‐dose regimens. Low trough concentrations (< 12 ng/mL) were associated with an increased risk of thromboembolism. Among patients meeting the ELDERCARE‐AF criteria, low drug levels were more frequent with the 15 mg regimen than with the 30 mg regimen.
Sung‐Chun Tang   +8 more
wiley   +1 more source

Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation. [PDF]

open access: yesPLoS ONE, 2011
Variable warfarin response during treatment initiation poses a significant challenge to providing optimal anticoagulation therapy. We investigated the determinants of initial warfarin response in a cohort of 167 patients.
Inna Y Gong   +11 more
doaj   +1 more source

Performance Measures Using Electronic Health Records: Five Case Studies [PDF]

open access: yes, 2008
Presents the experiences of five provider organizations in developing, testing, and implementing four types of electronic quality-of-care indicators based on EHR data.
Brian L. Hazlehurst   +11 more
core  

Thromboprophylaxis in atrial fibrillation and association with cognitive decline: systematic review [PDF]

open access: yes, 2016
Objective:Atrial Fibrillation (AF) is associated with dementia. If AF-related cognitive decline is driven by cerebral embolic events, thromboprophylaxis may impact on this.
Lane, Deirdre A.   +4 more
core   +2 more sources

Incident heart failure: comparing management and outcome in primary and hospital settings in Western Sweden 2008–2017

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 832-838, April 2025.
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen   +4 more
wiley   +1 more source

Current issues in patient adherence and persistence: focus on anticoagulants for the treatment and prevention of thromboembolism

open access: yesPatient Preference and Adherence, 2010
Patrick P Kneeland, Margaret C FangThe University of California, San Francisco Division of Hospital Medicine, San Francisco, CA, USAAbstract: Warfarin therapy reduces morbidity and mortality related to thromboembolism. Yet adherence to long-term warfarin
Patrick P Kneeland, Margaret C Fang
doaj  

Ensemble of machine learning algorithms using the stacked generalization approach to estimate the warfarin dose

open access: yesPLoS ONE, 2018
Warfarin dosing remains challenging due to narrow therapeutic index and highly individual variability. Incorrect warfarin dosing is associated with devastating adverse events.
Zhiyuan Ma   +4 more
semanticscholar   +1 more source

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