Results 71 to 80 of about 102,210 (307)
Is home warfarin self-management effective? Results of the Randomised Self-Management of Anticoagulation Research Trial [PDF]
, 2013 Aims The Warfarin Self-Management Anticoagulation Research Trial (Warfarin SMART) was designed to determine whether patients self-managing warfarin (PSM) using the CoaguChek device and a dosing algorithm developed for the trial could keep the INR ...
Gebski, Val +5 more
core
Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
Warfarin Resistance: A Case Report
Eurasian Journal of Emergency Medicine, 2019 Warfarin is the most widely prescribed anticoagulant in the world. Patients who need more than 15 mg per day should be considered warfarin-resistant.
Uğur Gönlügür +3 more
doaj +1 more source
An albumin-derived peptide scaffold capable of binding and catalysis [PDF]
, 2012 We have identified a 101-amino-acid polypeptide derived from the sequence surrounding the IIA binding site of human albumin. The polypeptide contains residues that make contact with ligands as warfarin in the parent protein, and eight cysteine residues ...
SBLATTERO, DANIELE +30 more
core +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho +12 more
wiley +1 more source
Molecules, 2017 Human serum albumin (HSA) binds a variety of xenobiotics, including flavonoids and warfarin. The binding of another ligand to the IIA binding site on HSA can cause warfarin displacement and potentially the elevation of its free concentration in blood ...
Hrvoje Rimac +4 more
doaj +1 more source
Warfarin-induced deep vein thrombosis
, 2014 Khalid A Binymin,1 Magda Nasher,2 Dipti Patel2 1Liverpool University, Medical School, England, UK; 2Southport and Ormskirk NHS Trust, Southport District General Hospital, Kew, UK Abstract: We are presenting a 72-year-old female who was admitted to ...
Patel D, Binymin KA, Nasher M
core
Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal
, 2017 Warfarin is an oral anticoagulant, which is commonly used in the treatment and prophylaxis of thromboembolic conditions. Bleeding is the primary adverse effect associated with warfarin.
Hasan Ökmen +5 more
core +1 more source
, 2022 Introduction Due to various limitations of warfarin use, non-vitamin K oral anticoagulants have gradually become the first choice for the prevention of ischemic stroke. This article will comprehensively and systematically evaluate the efficacy and safety
Wei Xie +6 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang +5 more
wiley +1 more source