Results 81 to 90 of about 144,216 (270)
Molecules, 2017 Human serum albumin (HSA) binds a variety of xenobiotics, including flavonoids and warfarin. The binding of another ligand to the IIA binding site on HSA can cause warfarin displacement and potentially the elevation of its free concentration in blood ...
Hrvoje Rimac +4 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Mitral regurgitation (MR) is the valent type of valvular heart disease, caused by primary leaflet lesions or annular dilatation secondary to left ventricular dysfunction. It can lead to a series of complications such as volume overload, exacerbated pulmonary congestion, and heart failure, significantly impacting patient prognosis ...
Juelian Li +4 more
wiley +1 more source
Bound to bleed: How altered albumin binding may dictate warfarin treatment outcome
International Journal of Cardiology: Heart & Vasculature, 2019 Although non-vitamin-K anticoagulants are now the preferred option for stroke prevention in atrial fibrillation (AF), warfarin is still used in a significant number of patients.
Anke C. Fender, Dobromir Dobrev
doaj +1 more source
New oral anticoagulants and their reversal agents [PDF]
, 2018 Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients\u27 quality of life, not only due to the standard ...
Bodean, Oana +9 more
core +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Chronic thromboembolic pulmonary disease (CTEPD) leads to chronic total occlusions (CTOs) of the pulmonary arteries in a minority of patients. Treatment of CTOs with balloon pulmonary angioplasty (BPA) may substantially improve patient hemodynamics but presents unique technical challenges and has previously been associated with a ...
Elliot J. Stein +4 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) lower LDL cholesterol and may influence cancer through immunomodulatory pathways. However, their effect on human cancer incidence remains unknown. We conducted a retrospective, propensity score‐matched study (Clalit Health Services, Israel, 2010–2023) comparing PCSK9 ...
Inbar Nardi Agmon +10 more
wiley +1 more source
Bangladesh Journal of Pharmacology, 2008 Equilibrium dialysis was used to study in vitro binding of acetaminophen at physiological pH and temperature in Bovine serum albumin (BSA). The binding of acetaminophen and warfarin mixture was studied to determine the effect of acetaminophen on the ...
Md. Ashraful Alam +2 more
doaj +1 more source
Antithrombotic therapy with rivaroxaban in five patients with paroxysmal nocturnal haemoglobinuria and thrombotic events [PDF]
, 2018 Five patients with paroxysmal nocturnal haemoglobinuria and thrombotic complications under oral antithrombotic treatment with vitamin K antagonist were switched to receive the direct oral anticoagulant rivaroxaban an factor Xa inhibitor.
Cafolla, Arturo +4 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Target trial emulation of a multi‐institutional electronic health record network showed comparable cardiorenal effectiveness and safety of dapagliflozin versus empagliflozin in adults with type 2 diabetes and advanced‐stage chronic kidney disease.
Shih‐Hsuan Lin +6 more
wiley +1 more source