Results 161 to 170 of about 28,454 (216)
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Heritable Resistance to Warfarin in Rats
Nature, 1967WARFARIN and other anticoagulants are used for the destruction of rats throughout the world and have been by far the most successful materials ever introduced for this purpose. Since 1960, however, apparently independent outbreaks of resistance to warfarin in Rattus norvegicus have been reported from Scotland1, Denmark2 and Wales3.
J H, Greavses, P, Ayres
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Resistance to Warfarin in the Common Rat
Nature, 1964A CASE of apparent resistance of the common rat to warfarin occurred in 1958 on a farm in West Scotland1, and further evidence of resistance from the same farm was given in 1963 (ref. 2). No other report on this matter is known to me.
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Drug Intelligence & Clinical Pharmacy, 1983
Warfarin, a coumarin anticoagulant, acts by interfering with the hepatic synthesis of the vitamin-K-dependent clotting factors. It is used clinically in the treatment or prophylaxis of venous thrombosis and embolisms. Resistance to the effects of the coumarin and indanedione anticoagulants has been reported in rats and man, but its incidence has been
R J, Holt, C O, Freytes
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Warfarin, a coumarin anticoagulant, acts by interfering with the hepatic synthesis of the vitamin-K-dependent clotting factors. It is used clinically in the treatment or prophylaxis of venous thrombosis and embolisms. Resistance to the effects of the coumarin and indanedione anticoagulants has been reported in rats and man, but its incidence has been
R J, Holt, C O, Freytes
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Hereditary Warfarin Resistance
Southern Medical Journal, 1994We report on a case of hereditary warfarin resistance in a 27-year-old black man. Hereditary warfarin resistance is a rare disorder transmitted as autosomal dominant. It should be suspected in patients who require high doses of warfarin, achieve high plasma warfarin levels, and have a normal plasma warfarin clearance.
F, Diab, S, Feffer
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Malabsorption-associated warfarin resistance
American Journal of Health-System Pharmacy, 2009A case of malabsorption- associated warfarin resistance is reported.A 42-year-old, 111-kg, Caucasian man arrived at the emergency department with atypical pleuritic chest pain. The chest pain was associated with shortness of breath, diaphoresis, nausea, vomiting, and tachycardia.
Brian J, Sabol +2 more
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Warfarin resistance: biochemical evaluation of a warfarin-resistant wild brown rat
Biochemical Pharmacology, 1989We investigated the in vitro characteristics of the hepatic vitamin KO reductase of these rats to elucidate the type of ...
H H, Thijssen +2 more
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Warfarin Resistance Caused by Broccoli
New England Journal of Medicine, 1983openaire +3 more sources
Warfarin resistance due to malabsorption
Journal of Internal Medicine, 1994Abstract. A female patient developed warfarin resistance after 2 years of satisfactory therapy. Only a third of orally administered warfarin was absorbed, the clearance of warfarin was normal. The patient was also resistant for dicoumarol, while phenindione had satisfactory effect on the prothrombin time (PT).
I, Talstad, O N, Gamst
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Warfarin Resistance and Enteral Feedings
Journal of Parenteral and Enteral Nutrition, 1989Nutritional support via enteral feeding tubes may interfere with the response to medications by a number of mechanisms. A 31‐year‐old, white man was admitted after sustaining a gunshot wound to the chest and mandible. Subsequently, the patient developed pulmonary emboli documented by angiography.
J E, Martin, D M, Lutomski
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