Results 171 to 180 of about 2,357,394 (215)
Some of the next articles are maybe not open access.
Heritable Resistance to Warfarin in Rats
Nature, 1967WARFARIN and other anticoagulants are used for the destruction of rats throughout the world and have been by far the most successful materials ever introduced for this purpose. Since 1960, however, apparently independent outbreaks of resistance to warfarin in Rattus norvegicus have been reported from Scotland1, Denmark2 and Wales3.
J H, Greavses, P, Ayres
openaire +2 more sources
Warfarin Resistance and Enteral Feedings
Journal of Parenteral and Enteral Nutrition, 1989Nutritional support via enteral feeding tubes may interfere with the response to medications by a number of mechanisms. A 31‐year‐old, white man was admitted after sustaining a gunshot wound to the chest and mandible. Subsequently, the patient developed pulmonary emboli documented by angiography.
J E, Martin, D M, Lutomski
openaire +2 more sources
Warfarin Resistance with Nafcillin Therapy
Annals of Internal Medicine, 1984Drug-induced warfarin resistance may be mediated by the direct effect of a drug on warfarin's absorption, excretion, distribution, or metabolism. A 29-year-old man on long-term stable anticoagulation therapy with warfarin sodium developed resistance to warfarin while receiving nafcillin.
G D, Qureshi +3 more
openaire +2 more sources
Cardiovascular journal of Africa, 2008
Warfarin, the only available oral coumarin anticoagulant in South Africa, is widely prescribed for the prevention and management of arterial and venous thrombo-embolism. It has a narrow therapeutic index and a wide inter-individual variability in therapeutic response. Genetic polymorphism of the VKORC1 and CYP2C9 genes, as well as clinical factors such
P, Sinxadi, M, Blockman
openaire +1 more source
Warfarin, the only available oral coumarin anticoagulant in South Africa, is widely prescribed for the prevention and management of arterial and venous thrombo-embolism. It has a narrow therapeutic index and a wide inter-individual variability in therapeutic response. Genetic polymorphism of the VKORC1 and CYP2C9 genes, as well as clinical factors such
P, Sinxadi, M, Blockman
openaire +1 more source
Resistance to Warfarin in the Common Rat
Nature, 1964A CASE of apparent resistance of the common rat to warfarin occurred in 1958 on a farm in West Scotland1, and further evidence of resistance from the same farm was given in 1963 (ref. 2). No other report on this matter is known to me.
openaire +2 more sources
Warfarin resistance associated with nafcillin therapy
The American Journal of Medicine, 1989A woman with a history of diabetes mellitus, peptic ulcer disease, hypothyroidism, systemic lupus erythematous, and myasthenia gravis was admitted to the hospital for an elective thymectomy. She had a past history of deep venous thrombosis and received long-term anticoagulation therapy with warfarin.
G L, Fraser, M, Miller, K, Kane
openaire +2 more sources
Warfarin resistance in a French strain of rats
Journal of Biochemical and Molecular Toxicology, 2006AbstractA warfarin‐resistant strain and a warfarin‐susceptible strain of wild rats (Rattus norvegicus) maintained in enclosures of the National Veterinary School of Lyon (France) were studied to determine the mechanism of the resistance to anticoagulant rodenticides. A low vitamin K epoxide reductase (VKOR) activity has been reported for many resistant
Lasseur, Romain +5 more
openaire +3 more sources
Warfarin resistance in a chicago strain of rats
Biochemical Pharmacology, 1990A warfarin-resistant strain of rats trapped in Chicago was studied to determine the mechanism of the warfarin resistance. The Chicago-resistant rats (CR) differ from a Welsh-resistant strain (WR) which has a vitamin K epoxide reductase that is insensitive to warfarin. The epoxide and dithiol-dependent quinone reductases of the CR rats were as sensitive
T M, Misenheimer, J W, Suttie
openaire +2 more sources
Warfarin Resistance Associated With Parenteral Nutrition
The American Journal of the Medical Sciences, 2012Warfarin is widely used as an oral anticoagulant for the prevention and long-term treatment of venous thromboembolism and for the prevention of thromboembolic complications associated with atrial fibrillation, heart valve replacement and myocardial infarction.
Lily K, Cheung +2 more
openaire +2 more sources
Hereditary Warfarin Resistance
Archives of Internal Medicine, 1985• A 57-year-old black woman required a daily dosage of 50 mg of warfarin sodium to maintain her prothrombin time in a therapeutic range. The central volume of distribution and clearance of warfarin were normal for this patient. These findings, combined with the patient's requirement for plasma warfarin levels four times greater than those usually ...
openaire +1 more source