Results 21 to 30 of about 14,168 (156)

Potential of a Pharmacogenetic-Guided Algorithm to Predict Optimal Warfarin Dosing in a High-Risk Hispanic Patient

Journal of Investigative Medicine High Impact Case Reports, 2016
Deep abdominal vein thrombosis is extremely rare among thrombotic events secondary to the use of contraceptives. A case to illustrate the clinical utility of ethno-specific pharmacogenetic testing in warfarin management of a Hispanic patient is reported.
Dagmar F. Hernandez-Suarez MD, Karla Claudio-Campos BSc, Javier E. Mirabal-Arroyo MD, Bianca A. Torres-Hernández PhD, Angel López-Candales MD, FACC, FASE, Kyle Melin PharmD, Jorge Duconge PhD, BScPharm   +6 more
doaj   +1 more source

Cornus Mas and Urinary Tract Infections Treatment

Translational Research in Urology, 2020
Urinary tract infections (UTI) are somehow complicated to treat and patients frequently will have the problem of infection recurrence after complete cure.
Fatemeh Khatami, Fateme Guitynavard
doaj   +1 more source

Thrombosis secondary to protein-losing enteropathy (PLE): A case report and review

Thrombosis Update, 2021
Protein-losing enteropathy (PLE) is an uncommon diagnosis, caused by primary gastrointestinal disease, secondary to systemic disorders or an idiopathic condition. Little is known about its epidemiology, and it may be under-diagnosed, but case reports are
Sudeepthi Bandikatla, Satish Maharaj, Apaar Dadlani, Karishma Ramsubiek, Adam Rojan   +4 more
doaj   +1 more source

Anticoagulant resistance in Synanthropic rodents in the Stara Zagora region, Bulgaria

Macedonian Veterinary Review, 2019
The anticoagulant rodenticides are the most commonly used toxicants to control rodents nowadays. Therefore, developing resistance to them is an issue of great importance for pest control.
Georgi G. Zhelev, Kojcho P. Koev, Vladimir D. Dimitrov, Vladimir S. Petrov   +3 more
doaj   +1 more source

Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

Frontiers in Pharmacology, 2017
Existing algorithms account for ~50% of observed variance in warfarin dose requirements after including common polymorphisms. However, they do not perform as well in populations other than Caucasians, in part because some ethno-specific genetic variants ...
Karla Claudio-Campos, Aurora Labastida, Alga Ramos, Andrea Gaedigk, Jessicca Renta-Torres, Dariana Padilla, Giselle Rivera-Miranda, Stuart A. Scott, Stuart A. Scott, Gualberto Ruaño, Carmen L. Cadilla, Jorge Duconge-Soler   +11 more
doaj   +1 more source

Novel mutations in the VKORC1 gene of wild rats and mice – a response to 50 years of selection pressure by warfarin?

BMC Genetics, 2009
Background Coumarin derivatives have been in world-wide use for rodent pest control for more than 50 years. Due to their retarded action as inhibitors of blood coagulation by repression of the vitamin K reductase (VKOR) activity, they are the ...
Jäkel Thomas, Song Ki-Joon, MacNicoll Alan D, León Vanina, Menzel Sandra, Pelz Hans-Joachim, Rost Simone, Oldenburg Johannes, Müller Clemens R   +8 more
doaj   +1 more source

Rivaroxaban as an effective alternative to warfarin in a patient with atrial fibrillation, thrombophilia, and left atrial appendage thrombus: a case report

Journal of Medical Case Reports, 2017
Background Atrial fibrillation is the most common cardiac arrhythmia. It is responsible for up to 20% of all ischemic strokes. Rate control and anticoagulation are crucial for atrial fibrillation management and stroke prevention.
Michele Scarano, Matteo Casale, Cesare Mantini, Egidio Imbalzano, Cristiana Consorti, Daniela Clemente, Giuseppe Dattilo   +6 more
doaj   +1 more source

Maternal and Fetal Outcomes in Pregnant Women with a Prosthetic Mechanical Heart Valve

Clinical Medicine Insights: Cardiology, 2016
Background Pregnancy is associated with several cardiocirculatory changes that can significantly impact underlying cardiac disease. These changes include an increase in cardiac output, sodium, and water retention leading to blood volume expansion, and ...
Sherif W. Ayad, Mahmoud M. Hassanein, Elsayed A. Mohamed, Ahmed M. Gohar   +3 more
doaj   +1 more source

Field trials to assess resistance to warfarin and difenacoum of house mice in relation to the occurrence of variants in the vkorc1-gene before and after the treatments

Julius-Kühn-Archiv, 2011
House mice (Mus musculus domesticus) vary considerably in their susceptibility to anticoagulants, and several non-synonymous sequence variants in the coding region of the vitamin K epoxide reductase subcomponent 1 gene (vkorc1) were found in Germany ...
Endepols, S., Klemann, N., Song, Y., Kohn, M. H.   +3 more
doaj   +1 more source

Uncovering the Bone-Muscle Interaction and Its Implications for the Health and Function of Older Adults (the Wellderly Project): Protocol for a Randomized Controlled Crossover Trial

JMIR Research Protocols, 2021
BackgroundBone and muscle are closely linked anatomically, biochemically, and metabolically. Acute exercise affects both bone and muscle, implying a crosstalk between the two systems.
Smith, Cassandra, Lin, Xuzhu, Scott, David, Brennan-Speranza, Tara C, Al Saedi, Ahmed, Moreno-Asso, Alba, Woessner, Mary, Bani Hassan, Ebrahim, Eynon, Nir, Duque, Gustavo, Levinger, Itamar   +10 more
doaj   +1 more source