Results 11 to 20 of about 2,357,394 (215)

Warfarin Resistance: A Case Report [PDF]

Eurasian Journal of Emergency Medicine, 2019
Warfarin is the most widely prescribed anticoagulant in the world. Patients who need more than 15 mg per day should be considered warfarin-resistant.
Uğur Gönlügür, Tanseli Gönlügür, Öztürk Özdemir, Fatma Sılan   +3 more
doaj   +6 more sources

Warfarin Resistance, a Case Report [PDF]

Journal of Cardiovascular and Thoracic Research, 2010
In tolerance to oral anticoagulant drugs may arise as an inborn genetic defect resulting in insensitive hepatic receptor sites to oral anticoagulants or it may be due to one of several acquired causes such as noningestion or malabsorption of the drugs ...
Rezayat Parvizi, Nima Makhdami, Roshan Dinparasti   +2 more
doaj   +2 more sources

Warfarin Resistance Revisited [PDF]

Proceedings of the Vertebrate Pest Conference, 1998
Roughly 50 years ago, the Wisconsin Alumni Research Foundation developed warfarin, the first anticoagulant rodenticide. This product was something close to that desired elusive magic bullet of pest management. Warfarin effectively killed rats and mice,
Madigan, Constance Padula, Frantz, Stephen C.   +1 more
core   +5 more sources

Field trials to assess resistance to warfarin and difenacoum of house mice in relation to the occurrence of variants in the vkorc1-gene before and after the treatments [PDF]

Julius-Kühn-Archiv, 2011
House mice (Mus musculus domesticus) vary considerably in their susceptibility to anticoagulants, and several non-synonymous sequence variants in the coding region of the vitamin K epoxide reductase subcomponent 1 gene (vkorc1) were found in Germany ...
Endepols, S., Klemann, N., Song, Y., Kohn, M. H.   +3 more
doaj   +2 more sources

Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state. [PDF]

Blood Adv, 2023
Missense vitamin K epoxide reductase (VKOR) mutations in patients cause resistance to warfarin treatment but not abnormal bleeding due to defective VKOR activity. The underlying mechanism of these phenotypes remains unknown.
Li S, Sun J, Liu S, Zhou F, Gross ML, Li W.   +5 more
europepmc   +2 more sources

VKORC1 variants as significant predictors of warfarin dose in Emiratis

Pharmacogenomics and Personalized Medicine, 2019
Zeina N Al-Mahayri,1 Hayat S Al Jaibeji,2 Yolande Saab,3 Karem Soliman,4 Lihadh Al-Gazali,5 George P Patrinos,1,6–7 Bassam R Ali1,71Department of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United ...
Al-Mahayri ZN, Al Jaibeji HS, Saab Y, Soliman K, Al-Gazali L, Patrinos GP, Ali BR   +6 more
doaj   +1 more source

Azathioprine-Induced Warfarin Resistance [PDF]

Annals of Pharmacotherapy, 2008
To describe a case of azathioprine-induced warfarin resistance, present a literature review on warfarin-azathioprine interactions, and provide recommendations on appropriate management of this clinically significant interaction.A 29-year-old female with Cogan's syndrome experienced thrombosis of the left internal carotid artery. She was treated with an
Sara R, Vazquez, Matthew T, Rondina, Robert C, Pendleton   +2 more
openaire   +2 more sources

Chronic Thromboembolic Pulmonary Hypertension With Cold Agglutinins Needing Pulmonary Thromboendarterectomy: The Use of Therapeutic Plasma Exchange. [PDF]

Pulm Circ
ABSTRACT Cold agglutinins can be detected in patients with chronic thromboembolic pulmonary hypertension (CTEPH) during pulmonary thromboendarterectomy (PTE) pre‐operative testing. Peri‐operative management of these patients in anticipation of deep hypothermic circulatory arrest can be challenging and has not been standardized. We describe our relevant
Naqvi B, Bautista MA, Sanchez AP, Yang JZ, Fernandes TM, Poch DS, Kerr KM, Kim NH, Madani MM, Pretorius VG, Allen ES, Kopko PM, Dilly LD, Ginsberg C, Park SJ, Choi M, Cruz DN, Papamatheakis DG.   +17 more
europepmc   +2 more sources

Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC [PDF]

, 2011
Background: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset.
Förch, Christian, Waltraud Pfeilschifter, Daniel Spitzer, Pfeilschifter, Josef (Prof. Dr.), Helmuth Steinmetz, Spitzer, Daniel, Steinmetz, Helmuth, Steinmetz Helmuth, Christian Foerch, Pfeilschifter, Waltraud, Josef Pfeilschifter, Pfeilschifter Waltraud, Spitzer Daniel, Foerch Christian, Pfeilschifter Josef   +14 more
core   +2 more sources

High clearance of (S)‐warfarin in a warfarin‐resistant subject. [PDF]

British Journal of Clinical Pharmacology, 1993
A 30 year old black male required a 60 mg daily dose of warfarin to elicit a therapeutic anticoagulant response (normal warfarin dose 2.5‐ 10 mg day‐1; maximum 15 mg day‐1). Hereditary warfarin resistance was suspected after compliance, diet, concurrent medication and any gastrointestinal disorder were eliminated as contributory causes. The disposition
H O, Hallak, P J, Wedlund, M W, Modi, I H, Patel, G L, Lewis, B, Woodruff, A A, Trowbridge   +6 more
openaire   +2 more sources