Results 51 to 60 of about 509,079 (288)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The effect of self-selected versus standardised warm-ups on kayak ergometer performance in Hungarian elite kayakers: a randomized controlled crossover trial

open access: yesBMC Sports Science, Medicine and Rehabilitation
Background Warm-up strategies play a crucial role in enhancing athletic performance and preventing injuries, yet the optimal warm-up protocol for sprint kayaking remains unclear.
Emese Trájer   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Effects of Myofascial Release and Dynamic Warm-up on Exercise Performance [PDF]

open access: yes, 2012
Color poster with text, tables, and graphs.The purpose of this study was to compare the use of foam-rolling to dynamic warm-up on flexibility, power, speed, endurance, and balance in young recreationally active adults.University of Wisconsin--Eau Claire ...
Boesel, Chelsea   +4 more
core   +1 more source

Magnetars as cooling neutron stars with internal heating [PDF]

open access: yes, 2006
We study thermal structure and evolution of magnetars as cooling neutron stars with a phenomenological heat source in a spherical internal layer. We explore the location of this layer as well as the heating rate that could explain high observable thermal
A. D. Kaminker   +38 more
core   +3 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Comparison of the Immediate Effects of Modified and Routine WarmUps on Knee Joint Function and Dynamic Balance in Athletes

open access: yesJournal of Rehabilitation Sciences and Research, 2016
Background: Warm-up before a sport activity is the most common preventive measure to reduce the incidences and severity of injuries during sport activities.
Elham Hamoule, Mohsen Razeghi
doaj  

Improving Engine Oil Warm Up through Waste Heat Recovery

open access: yesEnergies, 2017
In the transportation sector, engine oil thermal management has not yet received the attention it deserves in the path towards carbon dioxide and pollutants reduction. During the homologation cycle (which represents a typical daily trip), oil temperature
Davide Di Battista, Roberto Cipollone
doaj   +1 more source

The effects of dynamic and static stretching methods on speed, agility and power [PDF]

open access: yes, 2009
INTRODUCTION: Warm-ups are integral to coaches’ and athletes’ preparations, yet current research and practice provides conflicting advice on the most effective warm-up procedure for aiding performance.
Bishop, Daniel
core   +1 more source

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