Results 41 to 50 of about 515,316 (299)
Thermo-micro-mechanical simulation of bulk metal forming processes
The newly proposed microstructural constitutive model for polycrystal viscoplasticity in cold and warm regimes (Motaman and Prahl, 2019), is implemented as a microstructural solver via user-defined material subroutine in a finite element (FE) software ...
Haase, Christian +3 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Concurrently improving the formability and post-formed strength of Al-Zn-Mg alloy sheets is crucial for producing high-strength parts with complex shapes.
Wan-Ling Chen, Rong-Shean Lee
doaj +1 more source
Thermo-mechanical forming of Al-Mg-Si Sheet [PDF]
In warm forming of aluminum sheet, the temperature and strain rates vary considerably. In simulations, the material\ud model must be capable to predict stresses within this wide range.
Boogaard, A.H. van den +3 more
core +1 more source
Response of A356 to warm rotary forming and subsequent T6 heat treatment
The through-process microstructural effects in A356 subjected to rotary forming at elevated temperatures have been investigated. Macro and micro-hardness testing have been used extensively to track changes in the material from the as-cast state to as ...
Maijer, D. M., Roy, M. J.
core +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
A material model for warm forming of aluminium sheet [PDF]
A material model has been developed to simulate the warm forming of Al–Mg\ud sheet. Both the hardening behaviour, including temperature and strain rate effects, and the\ud biaxial stress–strain response of the sheet are considered.
Bolt, P.J., Boogaard, A.H. van den
core +2 more sources
Simulations of disk galaxies with cosmic ray driven galactic winds
We present results from high-resolution hydrodynamic simulations of isolated SMC- and Milky Way-sized galaxies that include a model for feedback from galactic cosmic rays (CRs). We find that CRs are naturally able to drive winds with mass loading factors
Agertz, Oscar +3 more
core +1 more source
The Fate of High-Velocity Clouds: Warm or Cold Cosmic Rain? [PDF]
We present two sets of grid-based hydrodynamical simulations of high-velocity clouds (HVCs) traveling through the diffuse, hot Galactic halo. These HI clouds have been suggested to provide fuel for ongoing star formation in the Galactic disk.
Beck +50 more
core +3 more sources
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source

