Results 41 to 50 of about 61,624 (261)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Литьë и металлургия, 2006 Steel forming technology in conditions of warm forming is a process, which is very attractive for technological practice in term of lower energy consumption, higher quality of the surfase and dimensional precision of gorged pieces.
М. Kapustova, V. Tittel
doaj
The Influence of Heat and Holding Time on the Warm Forming of Al–Mg–Si Alloys
Journal of Manufacturing and Materials ProcessingWarm forming of heat-treatable aluminium alloys can induce significant changes in their initial heat treatment, affecting both the forming process and the final in-service properties.
Vasco Simões +3 more
doaj +1 more source
Effect of temperature and strain rate fluctuation on forming limit curve of 5083 Al-Mg alloy sheet
Advances in Mechanical Engineering, 2022 The temperature and strain rate have significant effect on the formability of Al-Mg alloy sheet during warm forming process. Forming limit curve (FLC) is widely used for predicting sheet failure in warm forming simulation. However, the current simulation
Bo Hou +3 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Warm-forming of pre-aged Al-Zn-Mg-Cu alloy sheet
Materials & Design, 2020 Aluminium alloys of the 7xxx series are attracting the attention of automakers due to their high specific strength. However, widespread use of 7xxx series alloys for the production of car parts from sheet metal has so far been prevented due to their low ...
Johannes A. Österreicher +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Advances in Industrial and Manufacturing Engineering, 2021 Tangential profile ring rolling (Profiled Radial Ring Rolling, PRRR) enables the fast and compared to machining inexpensive production of bearing rings or similar ring-shaped parts with near net-shape geometry and advantageous material properties due to ...
S. Hütter +5 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source