Results 121 to 130 of about 993,218 (302)

Precipitation-induced abrupt decrease of Siberian wildfire in summer 2022 under continued warming

open access: yesEnvironmental Research Letters
Wildfires in Northeast (NE) Siberia have become more frequent owing to the warming climate, exerting a profound impact on the global carbon cycle. While an increase in global temperature is recognized as a primary driver of unprecedented wildfires, the ...
Yeonsoo Cho   +7 more
doaj   +1 more source

The impact of a northern peatland on the earth’s radiative budget: sustained methane emission versus sustained carbon sequestration [PDF]

open access: yes, 2006
Northern peatlands sequester carbon and emit methane, and thus have both cooling and warming impacts on the climate system through their influence on atmospheric burdens of CO2 and CH4.
Frolking, Steve   +2 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Counting the cost of climate change at an agricultural level [PDF]

open access: yes
The effects of global climate change on agriculture will be diverse and complex. Some important qualitative conclusions emerge from the literature. First, it is important to focus on the rate at which climate changes and the capacity of farmers to adjust,
John Quiggin
core  

Americans’ Global Warming Beliefs and Attitudes [PDF]

open access: yes, 2013
This report presents results from a national study of what Americans understand about how the climate system works, and the causes, impacts, and potential solutions to global warming.
Anthony Leiserowitz   +4 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Big Burp: A Bad Day in the Paleocene [PDF]

open access: yes
This lesson focuses on global warming and a possible connection with the Paleocene extinction event. Students will explore how a global warming episode associated with the release of methane from methane hydrate deposits could have been responsible for ...

core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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