Results 111 to 120 of about 993,218 (302)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Experimental warming affects soil carbon dynamics in boreal and temperate forests: a meta-analysis
Environmental Research LettersBoreal and temperate forests, spanning cold mid- to high-latitude environments and encompassing about 43% of the global forest area, are highly vulnerable to warming.
Shan Xu +4 more
doaj +1 more source
Changes in Protein Levels during the Storage and Warming of Breast Milk in a Domestic Environment
ChildrenBackground/Objectives: Storage and warming can impact the protein concentration of breast milk (BM). This study aimed to explore the effects of routine BM handling, from storage to warming, on BM protein concentration.
Penprapa Siviroj +2 more
doaj +1 more source
, 2013 A thermodynamic device placed outdoors, or a local ecosystem, is subject to a variety of different temperatures given by short-tem (daily) and long-term (seasonal) variations.
Beck, Christian, Yalcin, G. Cigdem
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Ecology and EvolutionClimate change alters environmental conditions in ways that directly and indirectly affect plants. Flowering plants, for example, modify reproductive allocation in response to heat and drought stress, and such changes can in turn affect pollinator ...
Jess Gambel, David A. Holway
doaj +1 more source
Foraging by forest ants under experimental climatic warming: a test at two sites
Ecology and Evolution, 2013 Climatic warming is altering the behavior of individuals and the composition of communities. However, recent studies have shown that the impact of warming on ectotherms varies geographically: species at warmer sites where environmental temperatures are ...
Katharine L. Stuble +5 more
doaj +1 more source
French birds lag behind climate warming [PDF]
, 2007 Biodiversity responses to climate warming have been documented through the study of changes in distributions, abundances or phenologies of individual species or in more integrated measures such as species community richness and composition.
Denis Couvet +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source