Results 91 to 100 of about 481,746 (305)
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
International environment agreements and the case of global warming [PDF]
First, this article uses standard welfare economics to illustrate the market failure and policy coordination problems caused by transboundary pollution problems in general and global warming in particular.
Johan Eyckmans
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
What do Students and Households Think About Global Warming?
, 2010 Color poster with text, images, and graphs.Global warming has become a hotlydebated topic with much discussion occurring worldwide. The US is currently considering passing legislation mandating reductions in carbon emissions possibly coupled with taxes ...
Stroik, Paul +3 more
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Saving the Planet and Creating Jobs: W3 Atlantic Forum 2011 - Agenda
, 2011 Agenda from a two-day conference held at St Thomas University on September 29-30 2011.Work in a Warming World ...
Work in a Warming World (W3)
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Positive feedback between microclimate and shrub encroachment in the northern Chihuahuan desert
Ecosphere, 2010 Woody plant encroachment is affecting vegetation composition in arid grasslands worldwide and has been associated with a number of environmental drivers and feedbacks. It has been argued that the relatively abrupt character (both in space and in time) of
Paolo D'Odorico +7 more
doaj +1 more source