Results 41 to 50 of about 982,809 (281)

On the application and extension of Harten's high resolution scheme [PDF]

open access: yes, 1982
Extensions of a second order high resolution explicit method for the numerical computation of weak solutions of one dimensonal hyperbolic conservation laws are discussed.
Harten, A., Warming, R. F., Yee, H. C.
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Coupling between Ribotypic and Phenotypic Traits of Protists across Life Cycle Stages and Temperatures

open access: yesMicrobiology Spectrum, 2021
Relationships between ribotypic and phenotypic traits of protists across life cycle stages remain largely unknown. Herein, we used single cells of two soil and two marine ciliate species to examine phenotypic and ribotypic traits and their relationships ...
Songbao Zou   +5 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Spatiotemporal Analysis of Thermal Environment and Land Use Change in Sonipat, Panipat, and Jhajjar Districts Under the Central Circle Forest Area of Haryana, India (1993–2023)

open access: yesUrban Science
Changes in land use patterns due to urbanisation impact local weather patterns by influencing Land Surface Temperatures (LSTs). Despite rapid urbanisation in the Delhi-NCR (National Capital Region), the peri-urban fringes of Haryana, such as the Central ...
Himanshi Sharma   +3 more
doaj   +1 more source

Seasonal Volatile Emission Patterns of the Endemic New Zealand Shrub Dracophyllum subulatum on the North Island Central Plateau

open access: yesFrontiers in Plant Science, 2021
Volatile organic compounds (VOCs) produced by plants are essential indicators of their physiological response to environmental conditions. But evidence of natural variation in VOC emissions and their contributing factors is still limited, especially for ...
Evans Effah   +5 more
doaj   +1 more source

Foehn warming distributions in nonlinear and linear flow regimes: a focus on the Antarctic Peninsula [PDF]

open access: yes, 2014
The structure of lee-side warming during foehn events is investigated as a function of cross-barrier flow regime linearity. Two contrasting cases of westerly flow over the Antarctic Peninsula (AP) are considered – one highly nonlinear, the other ...
Elvidge, Andrew   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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