Results 151 to 160 of about 39,109 (309)

The Pharmacokinetics of Intravenous and Subcutaneous Ondansetron in Female Beagle Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The purpose of this study was to evaluate the pharmacokinetic profile of ondansetron following intravenous (IV) and subcutaneous (SC) administration in five healthy adult female Beagles. Dogs were administered ondansetron at 0.5 mg/kg IV and SC in a randomized crossover design.
Elena D. Landau, Kendal R. Boege, Kristen Messenger, Gregory Ballash, Daniel Gustafson, Carolina Ricco Pereira, Krista Banks, Turi Aarnes, Phillip Lerche, Monica Midon, Kirk A. Muñoz   +10 more
wiley   +1 more source

Comparison of flying qualities derived from in-flight and ground-based simulators for a jet-transport airplane for the approach and landing pilot tasks [PDF]

The primary objective was to provide information to the flight controls/flying qualities engineer that will assist him in determining the incremental flying qualities and/or pilot-performance differences that may be expected between results obtained via ...
Grantham, William D.
core   +1 more source

Nutrition Strategies for Next‐Generation Incretin Therapies: A Systematic Scoping Review of the Current Evidence

Obesity Reviews, EarlyView.
ABSTRACT Next‐generation incretin therapies, including semaglutide and tirzepatide, have transformed obesity and Type 2 diabetes management. However, evidence‐based nutritional strategies to support safe and effective use of these agents remain limited.
Marie Spreckley, Cara F. Ruggiero, Adrian Brown   +2 more
wiley   +1 more source

Cervical epidural catheter for administration of detomidine and morphine in a model of carpal synovitis in the horse

Veterinary Surgery, EarlyView.
Abstract Objective To determine the analgesic effects of detomidine and morphine administered by cervical epidural catheter (CEC) on a model of thoracic limb pain. Study design Prospective, randomized, blinded crossover study. Animals Five adult horses.
Veronica L. Edwards, Rachel Reed, Michael Perlini, Valerie J. Moorman   +3 more
wiley   +1 more source

Tracer Test as a Tool for Optimizing the Flow Patterns and Efficiency of a Full‐Scale Drainage Water Treatment Wetland

Water and Environment Journal, EarlyView.
Tracer testing assessed hydraulics and nitrate removal in three full‐scale agricultural drainage treatment wetlands over 3.5 years (three tests). The first test showed rapid, short‐circuited flow and low residence time. After modifying the collection system, the second test increased residence time from 1 to 7 days.
Jan Kukačka, Michal Šereš, Petr Fučík, Tereza Hnátková, Adam Sochacki, Markéta Kaplická, Ljuba Zídková, Jan Vymazal   +7 more
wiley   +1 more source

Application of frequency domain handling qualities criteria to the longitudinal landing task [PDF]

Under NASA sponsorship, an in-flight simulation of the longitudinal handling qualities of several configurations for the approach and landing tasks was performed on the USAF/AFWAL Total In-Flight Simulator by the Calspan Corporation.
Powers, B. G., Sarrafian, S. K.
core   +1 more source

Exercise‐induced dynamic hyperinflation in chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease caused by inhalation of noxious particles, most commonly cigarette smoking. The consequent changes in airways, lung parenchyma and pulmonary vasculature lead to increased resistive, elastic and threshold loads and impaired capacity of the respiratory muscle pump. COPD
Rebecca F. D'Cruz, Dominic Wilkins, Caroline J. Jolley   +2 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

Advanced piloted aircraft flight control system design methodology. Volume 2: The FCX flight control design expert system [PDF]

The development of a comprehensive and electric methodology for conceptual and preliminary design of flight control systems is presented and illustrated.
Mcruer, Duane T., Myers, Thomas T.
core   +1 more source

Time‐course analysis of cerebral circulation and cardiorespiratory responses to acute central blood volume reduction in healthy young males

Experimental Physiology, EarlyView.
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley, Tomoki Watada, Go Ito, Ai Shimada, Toru Sawai, Hideomi Nakata, Shingo Otsuki, Tadayoshi Miyamoto   +7 more
wiley   +1 more source