Disentangling Cognitive Load From Visual Reflexes: An Iso-Luminant Framework for Virtual Reality (VR)-Based Pupillometry. [PDF]
Yilmaz U +4 more
europepmc +1 more source
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) often presents with cervical lymph node metastasis, with 1%–4% of cases presenting as cancer of unknown primary (CUP). CUP poses diagnostic and therapeutic challenges and is linked to poorer survival outcomes.
Robin W. Jansen +7 more
wiley +1 more source
Aloin attenuates NMDA receptor by modulating calcium response on substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice. [PDF]
Tran TQN +4 more
europepmc +1 more source
Reinforcement drives within- not between-trial motor adaptation. [PDF]
Lehnberg FM +5 more
europepmc +1 more source
Notch-induced lateral inhibition compared to standard amplification lateral inhibition therapy for the treatment of chronic tinnitus: A randomised controlled trial. [PDF]
Quemar A +6 more
europepmc +1 more source
Schematic illustration on a therapeutic strategy wherein engineered extracellular vesicles (EVs) are delivered intranasally and specifically target pericytes. In a model of chronic cerebral hypoperfusion (BCAS), this targeted approach preserves cerebral blood flow, reinforces blood‐brain barrier (BBB) integrity, stabilizes the neurovascular unit (NVU),
Weiwei Shen +11 more
wiley +1 more source
Photobiomodulation mechanisms: duration of action in the human prefrontal cortex. [PDF]
O'Connor P +3 more
europepmc +1 more source
Abstract The pathological expansion of the polyglutamine (polyQ) repeat within the first exon of huntingtin (Httex1) protein is a defining hallmark of Huntington's disease (HD). Multiple evidence supports that the membrane recruitment of Httex1 is critical for its self‐assembly and related toxicity in HD.
Tânia Sousa +6 more
wiley +1 more source
Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions. [PDF]
Chaubal AS +5 more
europepmc +1 more source
Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems +5 more
wiley +1 more source

