Results 1 to 10 of about 22,724 (115)

Patient-Reported Outcomes After Neoadjuvant Therapy and Watch-and-Wait for Rectal Cancer: A Systematic Review and Meta-Analysis [PDF]

Annals of Surgery Open
Objective:. To evaluate patient-reported outcomes (PROs) in rectal cancer patients who underwent neoadjuvant therapy followed by watch-and-wait. Background:.
Bailey K. Hilty Chu, MD, Anthony Loria, MD, Totadri Dhimal, MD, Lydia Rafferty, MD, Marie Jacobs, MD, Megan Boyer, MD, Paula Cupertino, PhD, Fernando Colugnati, PhD, Erika Ramsdale, MD, Fergal Fleming, MD   +9 more
doaj   +2 more sources

Long-term anorectal function in rectal cancer patients managed by a watch-and-wait strategy after total neoadjuvant treatment: a cross-sectional study [PDF]

Radiation Oncology
Background This study evaluates the long-term anorectal function and rectal toxicity in rectal cancer patients who achieved a clinical complete response (cCR) to total neoadjuvant treatment (TNT) and were managed with a watch-and-wait (W&W) approach ...
Lan-yue Xu, Xin Jin, Hui Zhang, Xian Wu, Yan Xuan, Yun Deng, Jing-wen Wang, Zhi-yuan Zhang, Fan Xia, Zhen Zhang   +9 more
doaj   +2 more sources

A Case of Local Resection of Secondary Perianal Paget Disease Appearing during “Watch and Wait” Management of Locally Advanced Rectal Cancer after Preoperative Chemoradiotherapy [PDF]

Journal of the Anus, Rectum and Colon
A 78-year-old woman was diagnosed with lower rectal cancer extending to the dentate line. She underwent preoperative chemoradiotherapy, which resulted in tumor shrinkage and clinical complete response (cCR), leading to the implementation of the “Watch ...
Takahiro Amano, Toshiki Mukai, Masashi Akiya, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Senzo Taguchi, Tomohiro Yamaguchi, Akiko Chino, Tomoyuki Yano, Hiroshi Kawachi, Takashi Akiyoshi   +11 more
doaj   +2 more sources

Current Status of “Watch-and-Wait” Rectal Cancer Treatment in Asia-Pacific Countries [PDF]

Annals of Coloproctology, 2020
Purpose Current acceptance of the watch-and-wait (W&W) approach by surgeons in Asia-Pacific countries is unknown. An international survey was performed to determine status of the W&W approach on behalf of the Asia-Pacific Federation of Coloproctology ...
Jung Wook Huh, Kotaro Maeda, Zheng Liu, Xishan Wang, April Camilla Roslani, Woo Yong Lee   +5 more
doaj   +1 more source

Watch and Wait, Worth It?

Journal of Coloproctology, 2022
Background The surgery with total mesorectal excision recommended by R. J. Heald in 1982 is the gold standard. Rectal cancer (RC) surgery has a morbidity rate ranging from 6 to 35%, and it can cause functional issues such as sexual, urinary, and bowel ...
Manoel Álvaro de Freitas Lins Neto, Luís Henrique Alves Salvador Filho, Jorge Artur Peçanha de Miranda Coelho, João Otávio de Moraes Rolim   +3 more
doaj   +1 more source

The watch-and-wait strategy versus surgical resection for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy

Radiation Oncology, 2021
Background The watch-and-wait strategy offers a non-invasive therapeutic alternative for rectal cancer patients who have achieved a clinical complete response (cCR) after chemoradiotherapy.
Qiao-xuan Wang, Rong Zhang, Wei-wei Xiao, Shu Zhang, Ming-biao Wei, Yong-heng Li, Hui Chang, Wei-hao Xie, Li-ren Li, Pei-rong Ding, Gong Chen, Zhi-fan Zeng, Wei-hu Wang, Xiang-bo Wan, Yuan-hong Gao   +14 more
doaj   +1 more source

Watch and wait strategies for rectal cancer: A systematic review [PDF]

Precision and Future Medicine, 2022
Watch and wait (WW) strategies have been suggested for patients with clinical complete regression (cCR). The WW approach was first introduced by Habr–Gama in patients with cCR after neoadjuvant treatment. Actually, it is not “no surgery” but “deferral of
In Ja Park
doaj   +1 more source

Nonoperative versus operative approach according to the response to neoadjuvant chemoradiotherapy for rectal cancer: A prospective cohort study

Clinical and Translational Radiation Oncology, 2022
Purpose: To report on organ preservation following chemoradiotherapy (CRT) in a prospective cohort of locally advanced rectal cancer patients. Methods and materials: Fifty-two patients received CRT.
Philippe P. Bulens, Lien Smets, Annelies Debucquoy, Ines Joye, André D'Hoore, Albert Wolthuis, Lynn Debrun, Jeroen Dekervel, Eric Van Cutsem, Raphaëla Dresen, Vincent Vandecaveye, Christophe M. Deroose, Xavier Sagaert, Karin Haustermans   +13 more
doaj   +1 more source

A longitudinal cohort study of watch and wait in complete clinical responders after chemo-radiotherapy for localised rectal cancer: study protocol

BMC Cancer, 2022
Background Rectal Cancer is a common malignancy. The current treatment approach for patients with locally advanced rectal cancer involves neoadjuvant chemoradiotherapy followed by surgical resection of the rectum.
Sina Vatandoust, David Wattchow, Luigi Sposato, Michael Z Michael, John Leung, Kirsten Gormly, Gang Chen, Erin L. Symonds, Jeanne Tie, Lito Electra Papanicolas, Susan Woods, Val Gebski, Kelly Mead, Aleksandra Kuruni, Christos S. Karapetis   +14 more
doaj   +1 more source

Long-term outcomes of patients with primary intestinal follicular lymphoma managed with watch-and-wait strategy

Scientific Reports, 2023
Patients with primary intestinal follicular lymphoma are often followed-up without a specific treatment, and this approach is called the “watch-and-wait approach.” However, the long-term outcomes of this patient group have not been sufficiently ...
Masaya Iwamuro, Takehiro Tanaka, Daisuke Ennishi, Kazuhiro Matsueda, Masao Yoshioka, Koji Miyahara, Chihiro Sakaguchi, Mamoru Nishimura, Teruya Nagahara, Tomohiko Mannami, Ryuta Takenaka, Shohei Oka, Masafumi Inoue, Hidetaka Takimoto, Tomoki Inaba, Sayo Kobayashi, Tatsuya Toyokawa, Hirofumi Tsugeno, Seiyuu Suzuki, Sachiko Sawada, Shouichi Tanaka, Takao Tsuzuki, Hiroyuki Okada   +22 more
doaj   +1 more source