Results 221 to 230 of about 13,072,871 (281)

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Biocontrol of L. monocytogenes with Selected Autochthonous Lactic Acid Bacteria in Raw Milk Soft-Ripened Cheese under Different Water Activity Conditions. [PDF]

Foods
Martín-Miguélez JM, Robledo J, Martín I, Castaño C, Delgado J, Córdoba JJ.   +5 more
europepmc   +1 more source

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Water activity and pseudo-activity coefficient of sorbed water

Journal of Food Engineering, 1990
Abstract The sorption isotherm can be represented by a plot of the logarithm of a pseudo-activity coefficient log f′ = loga w − log W against W, the weight of water per 100 g of dried substance. This plot demonstrates the polyphasic behaviour of the system. With reference to the curve for a w = 1, the chemical potentials Δμ Φ for the first
BRAIBANTI, Antonio, FISICARO, Emilia, Palmia, F.   +2 more
openaire   +2 more sources

Water Activation for Boosting Electrochemiluminescence

Angewandte Chemie International Edition, 2023
AbstractIn conventional luminol electrochemiluminescence (ECL) systems, hydrogen peroxide and dissolved oxygen are employed as typical co‐reactants to produce reactive oxygen species (ROS) for efficient ECL emission. However, the self‐decomposition of hydrogen peroxide and limited solubility of oxygen in water inevitably restrict the detection accuracy
Mengzhen Xi, Zhichao Wu, Zhen Luo, Ling Ling, Weiqing Xu, Runshi Xiao, Hengjia Wang, Qie Fang, Liuyong Hu, Wenling Gu, Chengzhou Zhu   +10 more
openaire   +2 more sources

Comprehensively active condensed water from vapors of plasmon-activated water

Chemical Engineering Journal, 2021
Abstract Water is the most environmentally friendly solvent, but bulk water is conventionally considered to be a bystander in reactions performed in it. For decades, scientists have been discussing the characteristics of water that differ from bulk water in special environments.
Shih-Hao Yu, Wei-Yu Kao, Fu-Der Mai, Hui-Yen Tsai, Yu-Chuan Liu   +4 more
openaire   +1 more source

Solubility of water in hydrocarbons as a function of water activity

Talanta, 1968
A method is described for determination of low solubilities of water in organic liquids (such as are used in solvent extraction) by vacuum distillation of a suitably sized equilibrated sample through magnesium perchlorate in a conventional weighing tube. Tritium tracer is used to estimate completeness of water absorption.
J W, Roddy, C F, Coleman
openaire   +2 more sources

Water Activity of Mammalian Tissues

Nature, 1958
SINCE the original report by Sabbatani1 that the freezing-point depression of various dog tissues is on the average 150 per cent greater than that of blood, there has been continued interest in the possibility that intracellular fluid is hypertonic to extracellular fluid. Collip2, Leovey and Kerpel-Fronius3, Gomori and Molnar4, and Pichotka et al.
L H, MAFFLY, A, LEAF
openaire   +2 more sources

ACTIVE RENAL WATER EXCRETION

The Lancet, 1967
Abstract Water-loading experiments on normal young adults support the view that active water excretion by the kidneys helps to maintain the constancy of extracellular osmolality.
T L, Dormandy, A, Robinson, E D, Wright
openaire   +2 more sources